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Inverse agonism gains weight
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Inverse agonism gains weight
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
author
Roger A H Adan
series ordinal
1
object named as
Roger A H Adan
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
author name string
Martien J H Kas
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
published in
Trends in Pharmacological Sciences
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
volume
24
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
page(s)
315-321
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
cites work
Mechanisms of inverse agonism at G-protein-coupled receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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inferred from DOI database lookup
AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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inferred from DOI database lookup
Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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Neomorphic agouti mutations in obese yellow mice
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
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Central nervous system control of food intake
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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High constitutive activity of native H3 receptors regulates histamine neurons in brain.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
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Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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inferred from DOI database lookup
Agouti-related protein prevents self-starvation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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inferred from DOI database lookup
Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing [...]
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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inferred from DOI database lookup
Tonic inhibition of food intake during inactive phase is reversed by the injection of the melanocortin receptor antagonist into the paraventricular nucleus of the hypothalamus and central amygdala of the rat.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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Several Mutations in the Melanocortin-4 Receptor Gene Including a Nonsense and a Frameshift Mutation Associated with Dominantly Inherited Obesity in Humans
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
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Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inverse agonism at heptahelical receptors: concept, experimental approach and therapeutic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association between an agouti-related protein gene polymorphism and anorexia nervosa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A polymorphism in the human agouti-related protein is associated with late-onset obesity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A role for the Agouti-Related Protein promoter in obesity and type 2 diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons from constitutively active mutants of G protein-coupled receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antagonist and agonist activities of the mouse agouti protein fragment (91-131) at the melanocortin-1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Agouti Protein Inhibits the Production of Eumelanin and Phaeomelanin in the Presence and Absence of α-Melanocyte Stimulating Hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
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Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
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Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The genetics of pigmentation: from fancy genes to complex traits
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
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The agouti gene: turned on to yellow
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sustained orexigenic effect of Agouti related protein may be not mediated by the melanocortin 4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900130-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0165-6147(03)00130-5
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
PubMed ID
12823958
1 reference
stated in
Europe PubMed Central
PubMed ID
12823958
retrieved
6 August 2017
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