(Q35163534)

6 August 2017

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title

The glutamatergic system and Alzheimer's disease: therapeutic implications (English)

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6 August 2017

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1

D Allan Butterfield

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6 August 2017

Chava B Pocernich

2

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6 August 2017

language of work or name

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1 January 2003

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6 August 2017

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6 August 2017

volume

17

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6 August 2017

issue

9

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6 August 2017

page(s)

641-652

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https://scigraph.springernature.com/pub.10.2165/00023210-200317090-00004

6 August 2017

exact match

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cites work

Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Energy metabolism in glutamatergic neurons, GABAergic neurons and astrocytes in primary cultures

1 reference

12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

12 December 2020

Evaluation of memantine for neuroprotection in dementia

1 reference

12 December 2020

Anticonvulsant preclinical profile of CHF 3381: dopaminergic and glutamatergic mechanisms

1 reference

12 December 2020

Expression patterns and regulation of glutamate transporters in the developing and adult nervous system

1 reference

12 December 2020

d-Cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-d-aspartate receptor-ionophore complex in Alzheimer brain

1 reference

12 December 2020

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

1 reference

12 December 2020

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

1 reference

12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

12 December 2020

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Spermidine potentiates dizocilpine-induced impairment of learning performance by rats in a 14-unit T-maze

1 reference

12 December 2020

Decreased glutamate + glutamine in Alzheimer's disease detected in vivo with (1)H-MRS at 0.5 T.

1 reference

12 December 2020

[Bis-ammonium adamantane derivatives--novel modulators of polyamine binding sites]

1 reference

12 December 2020

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

1 reference

12 December 2020

Adverse psychological impact, glutamatergic dysfunction, and risk factors for Alzheimer's disease.

1 reference

12 December 2020

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

12 December 2020

Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats.

1 reference

12 December 2020

Estrogen replacement therapy for Alzheimer disease in postmenopausal women

1 reference

12 December 2020

Excitatory amino acid receptors and synaptic plasticity

1 reference

12 December 2020

Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

1 reference

12 December 2020

Hormone replacement therapy in postmenopausal women with Alzheimer's disease: a randomized, prospective study

1 reference

12 December 2020

Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic?

1 reference

12 December 2020

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

1 reference

12 December 2020

Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study

1 reference

12 December 2020

1 reference

12 December 2020

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

1 reference

12 December 2020

Excitatory amino acid transporter EAAT-2 in tangle-bearing neurons in Alzheimer's disease.

1 reference

12 December 2020

Transgenic mice expressing Alzheimer amyloid precursor proteins.

1 reference

12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

12 December 2020

Estrogen levels do not correlate with improvement in cognition

1 reference

12 December 2020

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

12 December 2020

Striatal expression of glutamic acid decarboxylase gene in Alzheimer's disease.

1 reference

12 December 2020

Glutamine synthetase-induced enhancement of beta-amyloid peptide A beta (1-40) neurotoxicity accompanied by abrogation of fibril formation and A beta fragmentation

1 reference

12 December 2020

d-Cycloserine enhances implicit memory in Alzheimer patients.

1 reference

12 December 2020

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease

1 reference

12 December 2020

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

1 reference

12 December 2020

Estrogen protects primary cortical neurons from glutamate toxicity.

1 reference

12 December 2020

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

12 December 2020

Nutritional approaches to combat oxidative stress in Alzheimer's disease

1 reference

12 December 2020

Oxidative modification of glutamine synthetase by amyloid beta peptide.

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

Modulation of A(beta) peptides by estrogen in mouse models

1 reference

12 December 2020

Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy

1 reference

12 December 2020

In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42)

1 reference

12 December 2020

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

1 reference

12 December 2020

Spermidine antagonizes the inhibitory effect of huperzine A on [3H]dizocilpine (MK-801) binding in synaptic membrane of rat cerebral cortex

1 reference

12 December 2020

N-methyl-d-aspartate receptor-mediated processing of beta-amyloid precursor protein in rat hippocampal slices: in vitro--superfusion study

1 reference

12 December 2020

Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.

1 reference

12 December 2020

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

12 December 2020

NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus

1 reference

12 December 2020

Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: results of a placebo-controlled, double-blind, pilot study.

1 reference

12 December 2020

The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy

1 reference

12 December 2020

Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine).

1 reference

12 December 2020

Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease

1 reference

12 December 2020

The antioxidant vitamin E modulates amyloid beta-peptide-induced creatine kinase activity inhibition and increased protein oxidation: implications for the free radical hypothesis of Alzheimer's disease

1 reference

12 December 2020

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

12 December 2020

Dose escalation safety and tolerance study of the competitive NMDA antagonist selfotel (CGS 19755) in neurosurgery patients.

1 reference

12 December 2020

Donepezil versus vitamin E in Alzheimer's disease: Part 2: mild versus moderate-severe Alzheimer's disease.

1 reference

12 December 2020

Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies

1 reference

12 December 2020

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

12 December 2020

Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients

1 reference

12 December 2020

The role of glutamate in neurotransmission and in neurologic disease

1 reference

12 December 2020

Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.

1 reference

12 December 2020

Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?

1 reference

12 December 2020

7th International Conference on Alzheimer's Disease and Related Disorders. Washington, DC, USA. July 9-18, 2000. Abstracts

1 reference

12 December 2020

beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease

1 reference

12 December 2020

Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity

1 reference

12 December 2020

Infusion of (+) -MK-801 and memantine -- contrasting effects on radial maze learning in rats with entorhinal cortex lesion.

1 reference

12 December 2020

Alzheimer's amyloid beta-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity: protective effect of vitamin E.

1 reference

12 December 2020

Variant forms of neuronal glutamate transporter sites in Alzheimer's disease cerebral cortex.

1 reference

12 December 2020

Vitamin E and neurodegenerative disorders associated with oxidative stress

1 reference

12 December 2020

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

1 reference

12 December 2020

Microglial response to amyloid plaques in APPsw transgenic mice.

1 reference

12 December 2020

Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, short-term exploratory modulation and spatial memory in awake, freely moving rats.

1 reference

12 December 2020

The N-methyl-D-aspartate receptor complex in Alzheimer's disease: reduced regulation by glycine but not zinc

1 reference

12 December 2020

1 reference

12 December 2020

GABAergic deafferentation hypothesis of brain aging and Alzheimer's disease revisited

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12 December 2020

Glutamate transporter protein subtypes are expressed differentially during rat CNS development.

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12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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12 December 2020

Decreased inositol (1,4,5)-trisphosphate receptor levels in Alzheimer's disease cerebral cortex: selectivity of changes and possible correlation to pathological severity.

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12 December 2020

WISDOM. Will Australian women participate?

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12 December 2020

Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons

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12 December 2020

Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40).

1 reference

12 December 2020

No additional benefit of HRT on response to rivastigmine in menopausal women with AD.

1 reference

12 December 2020

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

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12 December 2020

APP processing and synaptic function

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12 December 2020

Glycine prodrug facilitates memory retrieval in humans

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12 December 2020

Memantine in moderate-to-severe Alzheimer's disease

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12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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12 December 2020

Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

1 reference

12 December 2020

D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats.

1 reference

12 December 2020

Effect on memory processing by D-cycloserine, an agonist of the NMDA/glycine receptor

1 reference

12 December 2020

Protective effects of ifenprodil against glutamate-induced neurotoxicity in cultured retinal neurons.

1 reference

12 December 2020

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

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12 December 2020

No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use.

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12 December 2020

Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase.

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12 December 2020

Estrogen enhances uptake of amyloid beta-protein by microglia derived from the human cortex

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12 December 2020

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

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12 December 2020

Neuron loss in APP transgenic mice

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12 December 2020

Advances in Alzheimer's disease

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12 December 2020

Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress

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12 December 2020

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo

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12 December 2020

17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron

1 reference

12 December 2020

Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease

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12 December 2020

Milacemide and Other Drugs Active at Glutamate NMDA Receptors as Potential Treatment for Dementia

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12 December 2020

Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease

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12 December 2020

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

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12 December 2020

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model.

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12 December 2020

Excitatory amino acids and Alzheimer's disease

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12 December 2020

Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease

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12 December 2020

Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists

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12 December 2020

Postsynaptic signaling and plasticity mechanisms

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12 December 2020

Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial

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12 December 2020

Signal-processing machines at the postsynaptic density

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12 December 2020

Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.

1 reference

12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

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12 December 2020

Animal models of Alzheimer's disease: glutamatergic denervation as an alternative approach to cholinergic denervation

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12 December 2020

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

1 reference

12 December 2020

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

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12 December 2020

Estradiol attenuation of beta-amyloid-induced toxicity: a comparison o.

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12 December 2020

High-dose estradiol improves cognition for women with AD: results of a randomized study

1 reference

12 December 2020

Effects of injected Alzheimer beta-amyloid cores in rat brain.

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12 December 2020

Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation

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12 December 2020

The Women’s Health Initiative Memory Study (WHIMS)

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12 December 2020

10.2165/00023210-200317090-00004

Identifiers

DOI

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Dimensions Publication ID

6 August 2017

1051877064

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