(Q35176389)

6 August 2017

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title

Melanosomes and MHC class II antigen-processing compartments: a tinted view of intracellular trafficking and immunity (English)

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6 August 2017

3

Graça Raposo

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6 August 2017

Michael S Marks

1

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6 August 2017

Alexander C Theos

series ordinal

2

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6 August 2017

publication date

1 January 2003

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6 August 2017

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6 August 2017

volume

27

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6 August 2017

issue

2-3

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6 August 2017

page(s)

409-426

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Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells

6 August 2017

cites work

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12 December 2020

Antigen processing for amateurs and professionals

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12 December 2020

Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome

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12 December 2020

The leucine-based sorting motifs in the cytoplasmic domain of the invariant chain are recognized by the clathrin adaptors AP1 and AP2 and their medium chains

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12 December 2020

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

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12 December 2020

The AP-3-dependent targeting of the melanosomal glycoprotein QNR-71 requires a di-leucine-based sorting signal.

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12 December 2020

Di-leucine signals mediate targeting of tyrosinase and synaptotagmin to synaptic-like microvesicles within PC12 cells.

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12 December 2020

The use of melanosomal proteins in the immunotherapy of melanoma

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12 December 2020

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

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12 December 2020

Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation

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12 December 2020

Melanosomes are specialized members of the lysosomal lineage of organelles.

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12 December 2020

Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes

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12 December 2020

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

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12 December 2020

Generation of CD8+ and CD4+ T-cell response to dendritic cells genetically engineered to express the MART-1/Melan-A gene

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12 December 2020

Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.

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12 December 2020

Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines

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12 December 2020

The gene mutated in cocoa mice, carrying a defect of organelle biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3 gene

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12 December 2020

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device

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12 December 2020

Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-rasHa oncogene

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12 December 2020

Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells

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12 December 2020

Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other".

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12 December 2020

Invariant chain induces a delayed transport from early to late endosomes

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12 December 2020

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

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12 December 2020

The melanosome: membrane dynamics in black and white

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12 December 2020

Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells.

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12 December 2020

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

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12 December 2020

Trafficking of MHC class II molecules in the late secretory pathway

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12 December 2020

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

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12 December 2020

A cytoplasmic sequence in human tyrosinase defines a second class of di-leucine-based sorting signals for late endosomal and lysosomal delivery

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12 December 2020

CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase

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12 December 2020

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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12 December 2020

Enhanced interaction of HLA-DM with HLA-DR in enlarged vacuoles of hereditary and infectious lysosomal diseases.

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12 December 2020

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

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12 December 2020

Hrs recruits clathrin to early endosomes

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12 December 2020

Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

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12 December 2020

Myosin Va bound to phagosomes binds to F-actin and delays microtubule-dependent motility

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12 December 2020

Trafficking of major histocompatibility complex class II molecules in human B-lymphoblasts deficient in the AP-3 adaptor complex

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12 December 2020

A role for a melanosome transport signal in accessing the MHC class II presentation pathway and in eliciting CD4+ T cell responses

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12 December 2020

The endocytic pathway: a mosaic of domains

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12 December 2020

Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene

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12 December 2020

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes

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12 December 2020

Mutation of a new gene causes a unique form of Hermansky-Pudlak syndrome in a genetic isolate of central Puerto Rico

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12 December 2020

B lymphocytes secrete antigen-presenting vesicles

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12 December 2020

Major histocompatibility complex class II compartments in human and mouse B lymphoblasts represent conventional endocytic compartments

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12 December 2020

Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

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12 December 2020

Retrovirally transduced human dendritic cells can generate T cells recognizing multiple MHC class I and class II epitopes from the melanoma antigen glycoprotein 100.

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12 December 2020

Rabs grab motors: defining the connections between Rab GTPases and motor proteins

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12 December 2020

Discoordinate surface expression of IFN-gamma-induced HLA class II proteins in nonprofessional antigen-presenting cells with absence of DM and class II colocalization.

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12 December 2020

Melanosomal proteins as melanoma-specific immune targets

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12 December 2020

Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells

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12 December 2020

Isolation of novel HLA-DR restricted potential tumor-associated antigens from the melanoma cell line FM3.

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12 December 2020

A dominant-negative clathrin mutant differentially affects trafficking of molecules with distinct sorting motifs in the class II major histocompatibility complex (MHC) pathway

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12 December 2020

Rab GTPases, intracellular traffic and disease.

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12 December 2020

Intracellular trafficking pathway of newly synthesized CD1b molecules

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12 December 2020

Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak syndrome

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12 December 2020

Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome

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12 December 2020

Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation

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12 December 2020

Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes

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12 December 2020

Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene

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12 December 2020

Chemical Composition and Terminology Of Specialized Organelles (Melanosomes and Melanin Granules) in Mammalian Melanocytes

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12 December 2020

The tyrosinase tail mediates sorting to the lysosomal compartment in MDCK cells via a di-leucine and a tyrosine-based signal.

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12 December 2020

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

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12 December 2020

Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components

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12 December 2020

Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

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12 December 2020

Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients

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12 December 2020

Hermansky-Pudlak syndrome and related disorders of organelle formation

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12 December 2020

Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

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12 December 2020

Endocytosis and molecular sorting

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12 December 2020

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12 December 2020

nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts

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12 December 2020

In vitro and in vivo induction of a Th cell response toward peptides of the melanoma-associated glycoprotein 100 protein selected by the TEPITOPE program

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12 December 2020

The role of CD4+ T cell responses in antitumor immunity

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12 December 2020

The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins

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12 December 2020

Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1).

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12 December 2020

The biogenesis and functions of exosomes

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12 December 2020

Current understanding on the role of retinal pigment epithelium and its pigmentation

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12 December 2020

Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles

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12 December 2020

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

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12 December 2020

Characterization and subcellular localization of human Pmel 17/silver, a 110-kDa (pre)melanosomal membrane protein associated with 5,6,-dihydroxyindole-2-carboxylic acid (DHICA) converting activity.

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12 December 2020

The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts

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12 December 2020

Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis

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12 December 2020

gp100/pmel17 and tyrosinase encode multiple epitopes recognized by Th1-type CD4+T cells

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12 December 2020

Recycling MHC class I molecules and endosomal peptide loading

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12 December 2020

The central role of CD4(+) T cells in the antitumor immune response

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12 December 2020

T cell immune responses against melanoma and melanocytes in cancer and autoimmunity

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12 December 2020

The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis

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12 December 2020

Recombinant gamma-interferon induces changes in expression and shedding of antigens associated with normal human melanocytes, nevus cells, and primary and metastatic melanoma cells

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12 December 2020

Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen

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12 December 2020

Late endosomes: sorting and partitioning in multivesicular bodies.

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12 December 2020

Intracellular transport of MHC class II and associated invariant chain in antigen presenting cells from AP-3-deficient mocha mice

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12 December 2020

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

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12 December 2020

Antigen loading of MHC class I molecules in the endocytic tract

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12 December 2020

Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus protein

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12 December 2020

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

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12 December 2020

The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndrome

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12 December 2020

Human tumor antigens for cancer vaccine development

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12 December 2020

The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis

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12 December 2020

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

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12 December 2020

Biochemical control of melanogenesis and melanosomal organization

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12 December 2020

Mouse pale ear (ep) is homologous to human Hermansky-Pudlak syndrome and contains a rare 'AT-AC' intron

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12 December 2020

Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells.

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12 December 2020

Expression of major histocompatibility complex class II molecules in HeLa cells promotes the recruitment of AP-1 Golgi-specific assembly proteins on Golgi membranes

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12 December 2020

Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation

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12 December 2020

Early endosomes are required for major histocompatiblity complex class II transport to peptide-loading compartments

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12 December 2020

Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells.

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12 December 2020

Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis

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12 December 2020

Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic mice

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12 December 2020

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

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12 December 2020

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

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12 December 2020

The beta3A subunit gene (Ap3b1) of the AP-3 adaptor complex is altered in the mouse hypopigmentation mutant pearl, a model for Hermansky-Pudlak syndrome and night blindness

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12 December 2020

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

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12 December 2020

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes

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12 December 2020

Identifiers

DOI

10.1385/IR:27:2-3:409

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Dimensions Publication ID

6 August 2017

1028682527

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