(Q35190124)

7 August 2017

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title

Chemical discovery and global gene expression analysis in zebrafish (English)

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7 August 2017

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Sophie Laurenson

2

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Don Love

object named as

Donald R Love

6

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Brent R Copp

object named as

Brent R Copp

5

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author name string

Franz B Pichler

1

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7 August 2017

Liam C Williams

3

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7 August 2017

Andrew Dodd

4

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7 August 2017

publication date

1 August 2003

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7 August 2017

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7 August 2017

volume

21

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7 August 2017

issue

8

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7 August 2017

page(s)

879-883

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Chemical genomics: discovery of disease genes and drugs

7 August 2017

cites work

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7 January 2021

Transgenic systems in drug discovery: from target identification to humanized mice

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7 January 2021

Perspectives and challenges for DNA microarrays in drug discovery and development

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7 January 2021

Knockouts model the 100 best-selling drugs--will they model the next 100?

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7 January 2021

Headwaters of the zebrafish -- emergence of a new model vertebrate

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7 January 2021

From Zebrafish to human: modular medical models

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7 January 2021

Vertebrate development: a view from the zebrafish

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7 January 2021

Arteries and veins: making a difference with zebrafish

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7 January 2021

Streptococcus-zebrafish model of bacterial pathogenesis

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7 January 2021

Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development

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7 January 2021

Morpholino oligos: making sense of antisense?

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7 January 2021

Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo

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7 January 2021

A window to the heart: can zebrafish mutants help us understand heart disease in humans?

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7 January 2021

Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

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7 January 2021

The zebrafish as a tool for understanding the biology of visual disorders

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7 January 2021

Visualizing normal and defective bone development in zebrafish embryos using the fluorescent chromophore calcein

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7 January 2021

Zebrafish as a model for hearing and deafness.

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7 January 2021

Zebrafish as a cancer model system

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7 January 2021

Myc-induced T cell leukemia in transgenic zebrafish

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7 January 2021

Transgenic zebrafish model of neurodegeneration.

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7 January 2021

The dystrophin associated protein complex in zebrafish

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7 January 2021

Sarcoglycans of the zebrafish: orthology and localization to the sarcolemma and myosepta of muscle

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7 January 2021

Flies and fish: birds of a feather

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7 January 2021

Modelling human diseases in Drosophila and Caenorhabditis

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7 January 2021

The chicken as a model for large-scale analysis of vertebrate gene function.

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7 January 2021

The transformation of the model organism: a decade of developmental genetics

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7 January 2021

Zebrafish comparative genomics and the origins of vertebrate chromosomes

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7 January 2021

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7 January 2021

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

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7 January 2021

Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle

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7 January 2021

Microarrays and polyglutamine disorders: reports from the Hereditary Disease Array Group

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7 January 2021

An oligonucleotide fingerprint normalized and expressed sequence tag characterized zebrafish cDNA library

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7 January 2021

DNA microarray analyses of genes elicited by ultrasound in human U937 cells.

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7 January 2021

Chemical genomics in the global study of protein functions

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7 January 2021

Functional discovery via a compendium of expression profiles

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7 January 2021

Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response

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7 January 2021

Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.

1 reference

7 January 2021

The challenges of translating knockout phenotypes into gene function

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7 January 2021

Small molecule developmental screens reveal the logic and timing of vertebrate development

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7 January 2021

Dissection of angiogenic signaling in zebrafish using a chemical genetic approach

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7 January 2021

Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development

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7 January 2021

15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis

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7 January 2021

Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments

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7 January 2021

Rapid mapping of zebrafish mutations with SNPs and oligonucleotide microarrays

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7 January 2021

Apoptosis: definition, mechanisms, and relevance to disease

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7 January 2021

Evidence for apoptotic cell death in Alzheimer's disease.

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Basic local alignment search tool

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7 January 2021

Genes with homology to mammalian apoptosis regulators identified in zebrafish

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7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

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7 January 2021

Using mRNA expression profiling to determine anticancer drug efficacy

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7 January 2021

Identifiers

DOI

10.1038/NBT852

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7 August 2017

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