(Q35192878)

7 August 2017

title

Quantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition (English)

1 reference

7 August 2017

1 reference

Aman P Singh

1

1 reference

7 August 2017

Wojciech Krzyzanski

2

1 reference

7 August 2017

Steven W Martin

3

1 reference

7 August 2017

Gregory Weber

4

1 reference

7 August 2017

Alison Betts

5

1 reference

7 August 2017

Alaa Ahmad

6

1 reference

7 August 2017

Anson Abraham

7

1 reference

7 August 2017

Anup Zutshi

8

1 reference

7 August 2017

John Lin

9

1 reference

7 August 2017

Pratap Singh

10

1 reference

7 August 2017

language of work or name

English

0 references

publication date

3 December 2014

1 reference

7 August 2017

1 reference

7 August 2017

volume

17

1 reference

7 August 2017

issue

2

1 reference

7 August 2017

page(s)

389-399

1 reference

Prediction of human plasma concentration-time profiles of monoclonal antibodies from monkey data by a species-invariant time method

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Prediction of human pharmacokinetics of therapeutic monoclonal antibodies from simple allometry of monkey data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data: what have we learned?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Technological progresses in monoclonal antibody production systems.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Interspecies scaling of therapeutic monoclonal antibodies: initial look

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Estimation of population pharmacokinetic parameters of saquinavir in HIV patients with the MONOLIX software

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Elimination mechanisms of therapeutic monoclonal antibodies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Antibody pharmacokinetics and pharmacodynamics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Interspecies scaling of protein drugs: prediction of clearance from animals to humans

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Ways to fit a PK model with some data below the quantification limit

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Interspecies scaling of clearance and volume of distribution data for five therapeutic proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

A model-based approach to predicting the human pharmacokinetics of a monoclonal antibody exhibiting target-mediated drug disposition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Quantitative prediction of human pharmacokinetics for monoclonal antibodies: retrospective analysis of monkey as a single species for first-in-human prediction.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Translational pharmacokinetics and pharmacodynamics of an FcRn-variant anti-CD4 monoclonal antibody from preclinical model to phase I study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Prediction of human clearance of therapeutic proteins: simple allometric scaling method revisited.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4365083

Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis.

27 September 2018

1 reference

12 December 2020

Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis

1 reference

12 December 2020

Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis

1 reference

12 December 2020

Differential half-life of major histocompatibility complex encoded class I molecules in T and B lymphoblasts

1 reference

12 December 2020

Detection of very low receptor numbers on cells by flow cytometry using a sensitive staining method

1 reference

12 December 2020

The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis

1 reference

12 December 2020

Monoclonal antibody pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

10.1208/S12248-014-9690-8

Identifiers

DOI

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference