(Q35208583)

7 August 2017

1 reference

title

An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors (English)

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G protein-coupled receptor

7 August 2017

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author name string

Angela Cacace

1

1 reference

7 August 2017

Martyn Banks

2

1 reference

7 August 2017

Timothy Spicer

3

1 reference

7 August 2017

Francesca Civoli

4

1 reference

7 August 2017

John Watson

5

1 reference

7 August 2017

1 September 2003

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7 August 2017

1 reference

7 August 2017

8

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7 August 2017

785-792

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7 August 2017

17

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G protein-coupled receptors: dominant players in cell-cell communication

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Seven-transmembrane receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Activating and inactivating hormone receptor mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Polymorphic G-protein-coupled receptors and associated diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Protein-protein interactions at G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

G proteins: transducers of receptor-generated signals

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Receptor-effector coupling by G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Heterotrimeric G proteins: organizers of transmembrane signals

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

G-protein-coupled receptors and signaling networks: emerging paradigms.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

1 reference

7 January 2021

Ion-channel regulation by G proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Heptahelical receptor signaling: beyond the G protein paradigm.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

G-protein-independent signaling by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Signaling at zero G: G-protein-independent functions for 7-TM receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Drug discovery: a historical perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Functional Assays for Identifying Ligands at Orphan G Protein-Coupled Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Functional genomics: the search for novel neurotransmitters and neuropeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

G16 as a universal G protein adapter: implications for agonist screening strategies.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Chimaeric G alpha proteins: their potential use in drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Functional cell-based uHTS in chemical genomic drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Constitutive activity of G protein coupled receptors and drug action

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Agonist-independent regulation of constitutively active G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

The use of constitutively active GPCRs in drug discovery and functional genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Development of a homogeneous MAP kinase reporter gene screen for the identification of agonists and antagonists at the CXCR1 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Fusions to beta-lactamase as a reporter for gene expression in live mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Development of a dual glow-signal firefly and Renilla luciferase assay reagent for the analysis of G-protein coupled receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Functional coupling of endogenous serotonin (5-HT1B) and calcitonin (C1a) receptors in CHO cells to a cyclic AMP-responsive luciferase reporter gene

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Induction of NFAT-mediated transcription by Gq-coupled receptors in lymphoid and non-lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Reporter-gene systems for the study of G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

Cellular biosensors for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902809-5

7 January 2021

10.1016/S1359-6446(03)02809-5

Identifiers

DOI

1 reference

7 August 2017

1 reference