(Q35212611)

7 August 2017

title

Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics (English)

1 reference

7 August 2017

Johan Vande Voorde

13

0 references

Jubi John

Jubi John

10

0 references

Kalyan Das

Kalyan Das

2

0 references

Anita R Maguire

Anita R Maguire

17

0 references

Lieve Naesens

Lieve Naesens

15

0 references

Jan Balzarini

1

Jan Balzarini

1 reference

7 August 2017

18

Eddy Arnold

1 reference

7 August 2017

Jean A Bernatchez

3

1 reference

7 August 2017

Sergio E Martinez

4

1 reference

7 August 2017

Marianne Ngure

5

1 reference

7 August 2017

Sarah Keane

6

1 reference

7 August 2017

Alan Ford

7

1 reference

7 August 2017

Nuala Maguire

8

1 reference

7 August 2017

Niki Mullins

9

1 reference

7 August 2017

Youngju Kim

11

1 reference

7 August 2017

Wim Dehaen

12

1 reference

7 August 2017

Sandra Liekens

14

1 reference

7 August 2017

Matthias Götte

16

1 reference

7 August 2017

language of work or name

English

0 references

publication date

2 March 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

1 reference

7 August 2017

volume

112

1 reference

7 August 2017

issue

11

1 reference

7 August 2017

page(s)

3475-3480

1 reference

Design and synthesis of α-carboxy nucleoside phosphonate analogues and evaluation as HIV-1 reverse transcriptase-targeting agents

7 August 2017

cites work

1 reference

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Synthesis of nucleoside phosphate and phosphonate prodrugs

13 July 2018

1 reference

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Biased ligands: pathway validation for novel GPCR therapeutics

13 July 2018

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Mechanism of allosteric activation of SAMHD1 by dGTP

13 July 2018

1 reference

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Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion

13 July 2018

1 reference

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HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism

13 July 2018

1 reference

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Medicinal chemistry of nucleoside phosphonate prodrugs for antiviral therapy.

13 July 2018

1 reference

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Enzymatic regulation of cytosolic thymidine kinase 1 and mitochondrial thymidine kinase 2: a mini review

13 July 2018

1 reference

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The structure and function of G-protein-coupled receptors

13 July 2018

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Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors".

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Ribonucleotide reductases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

The G protein-coupled receptors: pharmacogenetics and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Structures of thymidine kinase 1 of human and mycoplasmic origin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

13 July 2018

1 reference

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DNA polymerases: structural diversity and common mechanisms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Ara-C: cellular and molecular pharmacology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Gemcitabine: preclinical pharmacology and mechanisms of action.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Properties of an affinity-column-purified human deoxycytidylate deaminase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Modulation of thymidine kinase activity: a biochemical strategy to enhance the activation of antineoplastic drugs.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Enzyme regulatory site-directed drugs: study of the interactions of 5'-amino-2', 5'-dideoxythymidine (5'-AdThd) and thymidine triphosphate with thymidine kinase and the relationship to the stimulation of thymidine uptake by 5'-AdThd in 647V cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Regulation of the activation of fluorodeoxyuridine by substrate competition and feedback inhibition in 647V cells

13 July 2018

1 reference

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Nucleic acid polymerases use a general acid for nucleotidyl transfer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance

26 September 2018

1 reference

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Mode of action of phosphonoformate as an anti-herpes simplex virus agent

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371953

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1420233112

Metal Activation of Enzymes in Nucleic Acid Biochemistry

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25733891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of deoxycytidine kinase by deoxycytidine and deoxycytidine 5' triphosphate in whole leukemia and tumor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25733891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1420233112

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference