(Q35219849)

7 August 2017

title

Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa (English)

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7 August 2017

11

Nagahisa Yoshimura

1 reference

7 August 2017

Hanako Ohashi Ikeda

1

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7 August 2017

Norio Sasaoka

2

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7 August 2017

Masaaki Koike

3

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7 August 2017

Noriko Nakano

4

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7 August 2017

Yuki Muraoka

5

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7 August 2017

Yoshinobu Toda

6

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7 August 2017

Tomohiro Fuchigami

7

1 reference

7 August 2017

Toshiyuki Shudo

8

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7 August 2017

Ayana Iwata

9

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7 August 2017

Seiji Hori

10

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7 August 2017

Akira Kakizuka

12

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7 August 2017

language of work or name

English

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publication date

6 August 2014

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7 August 2017

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7 August 2017

volume

4

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7 August 2017

page(s)

5970

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Creative Commons Attribution 4.0 International

7 August 2017

copyright license

start time

6 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Retinitis pigmentosa‑associated rhodopsin mutant T17M induces endoplasmic reticulum (ER) stress and sensitizes cells to ER stress-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

High-speed atomic force microscopic observation of ATP-dependent rotation of the AAA+ chaperone p97.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Randomized trial of ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for retinitis pigmentosa

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Endoplasmic reticulum stress sensing in the unfolded protein response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Real-time imaging of rabbit retina with retinal degeneration by using spectral-domain optical coherence tomography

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Stress management at the ER: regulators of ER stress-induced apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

The Cdc48 machine in endoplasmic reticulum associated protein degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Cdc48: a power machine in protein degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Exome sequencing reveals VCP mutations as a cause of familial ALS

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Enhanced ATPase activities as a primary defect of mutant valosin-containing proteins that cause inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Misfolded proteins and retinal dystrophies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Restoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

ER and aging-Protein folding and the ER stress response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Roles of VCP in human neurodegenerative disorders

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Role of the unfolded protein response in cell death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Retinal degeneration mutants in the mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

The glucose-regulated proteins: stress induction and clinical applications

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

PI3K: downstream AKTion blocks apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122966

Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration

13 July 2018

1 reference

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

21 January 2018

1 reference

The significance of external limiting membrane status for visual acuity in age-related macular degeneration

21 January 2018

1 reference

Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress

21 January 2018

1 reference

Binding of human BiP to the ER stress transducers IRE1 and PERK requires ATP.

21 January 2018

1 reference

ISCEV Standard for full-field clinical electroretinography (2008 update).

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/SREP05970

1 reference

7 August 2017

1 reference

7 August 2017

1 reference