(Q35229542)

7 August 2017

4 references

12 October 2019

20 November 2019

28 November 2019

6 December 2020

p66Shc aging protein in control of fibroblasts cell fate (English)

1 reference

Agnieszka Karkucinska-Wieckowska

7 August 2017

1 reference

12 October 2019

1 reference

20 November 2019

1 reference

28 November 2019

1 reference

6 December 2020

Agnieszka Karkucinska-Wieckowska

2

0 references

Carlotta Giorgi

Carlotta Giorgi

4

0 references

Joanna Szczepanowska

Joanna Szczepanowska

5

0 references

Jerzy Duszyński

Jerzy Duszynski

7

0 references

Maciej Pronicki

Maciej Pronicki

8

0 references

Mariusz R Wieckowski

Mariusz R Wieckowski

10

0 references

Paolo Pinton

Paolo Pinton

9

0 references

Magdalena Lebiedzinska

3

Magdalena Lebiedzinska

1 reference

7 August 2017

6

Gyorgy Szabadkai

1 reference

7 August 2017

Jan M Suski

1

1 reference

7 August 2017

language of work or name

English

0 references

publication date

22 August 2011

5 references

International Journal of Molecular Sciences

7 August 2017

12 October 2019

20 November 2019

28 November 2019

6 December 2020

5 references

7 August 2017

12 October 2019

20 November 2019

28 November 2019

6 December 2020

12

1 reference

7 August 2017

issue

8

1 reference

7 August 2017

page(s)

5373-5389

1 reference

Creative Commons Attribution 3.0 Unported

7 August 2017

copyright license

4 references

12 October 2019

20 November 2019

28 November 2019

The Shc locus regulates insulin signaling and adiposity in mammals

6 December 2020

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

An attempt to prevent senescence: a mitochondrial approach.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The p53-p66shc-Manganese Superoxide Dismutase (MnSOD) network: a mitochondrial intrigue to generate reactive oxygen species.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

p66Shc-generated oxidative signal promotes fat accumulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Ca2+ signaling, mitochondria and cell death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Effects of epigallocatechin-3-gallate on mitochondrial integrity and antioxidative enzyme activity in the aging process of human fibroblast

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Interaction of vitamins C and E as better cosmeceuticals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

p66(shc) is highly expressed in fibroblasts from centenarians.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Influence of a mitochondrial genetic defect on capacitative calcium entry and mitochondrial organization in the osteosarcoma cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Aging: a theory based on free radical and radiation chemistry

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Oxidative damage to mitochondria and aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Evolution of Shc functions from nematode to human

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Mitochondria as all-round players of the calcium game

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The p66shc adaptor protein controls oxidative stress response and life span in mammals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Coenzyme Q10, a cutaneous antioxidant and energizer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Mitochondrial dysfunction in the senescence accelerated mouse (SAM).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Oxidative stress, caloric restriction, and aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Decline with age of the respiratory chain activity in human skeletal muscle.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Extension of the Lifespan of Cultured Normal Human Diploid Cells by Vitamin E

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Cell culture studies on patients with mitochondrial diseases: molecular defects in pyruvate dehydrogenase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Respiratory chain defects in the mitochondria of cultured skin fibroblasts from three patients with lacticacidemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

The effects of dietary restriction on mitochondrial dysfunction in aging.

13 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Mitochondrial complex I defects in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

The effect of aging and increasing ascorbate concentrations on respiratory chain activity in cultured human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Respiratory chain analysis of skin fibroblasts in mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4,977 BP-deleted mitochondrial DNA.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179172

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

26 September 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS12085373

Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus)

21 January 2018

1 reference

12 December 2020

The Effect of Age on Mitochondrial Ultrastructure

1 reference

12 December 2020

Photoaging is associated with protein oxidation in human skin in vivo

1 reference

12 December 2020

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

12 December 2020

Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts

1 reference

12 December 2020

Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells

1 reference

12 December 2020

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

1 reference

12 December 2020

Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria

1 reference

12 December 2020

1 reference

12 December 2020

Liver mitochondrial respiratory functions decline with age

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS12085373

1 reference

7 August 2017

1 reference

7 August 2017

1 reference