(Q35257063)

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Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Jaroslav Malina

2

object named as

Jaroslav Malina

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

author name string

Hana Kostrhunova

1

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Amanda J Pickard

3

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Jana Stepankova

4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Marie Vojtiskova

5

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Jana Kasparkova

6

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Tereza Muchova

7

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Matthew L Rohlfing

8

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Ulrich Bierbach

9

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Viktor Brabec

10

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

language of work or name

0 references

publication date

17 August 2011

1 reference

Europe PubMed Central

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7 August 2017

Molecular Pharmaceutics

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1941-1954

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Organometallic half-sandwich iridium anticancer complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Excursions in polynuclear platinum DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Probing platinum-adenine-n3 adduct formation with DNA minor-groove binding agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Mechanism of transcriptional stalling at cisplatin-damaged DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

The resurgence of platinum-based cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Direct cellular responses to platinum-induced DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Adenine-N3 in the DNA minor groove - an emerging target for platinum containing anticancer pharmacophores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Photoactivatable platinum complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Biochemical mechanisms of cisplatin cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Looking at long molecules in solution: what happens when they are subjected to Couette flow?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Molecular aspects of antitumor effects of a new platinum(IV) drug.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Ruthenium complexes as anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Platinum-intercalator conjugates: from DNA-targeted cisplatin derivatives to adenine binding complexes as potential modulators of gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Effects of monofunctional adducts of platinum(II) complexes on thermodynamic stability and energetics of DNA duplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Platinum(IV) anticancer complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Cisplatin sensitivity in Hmbg1-/- and Hmbg1+/+ mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG box proteins and nucleotide excision repair of these adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Recognition of cisplatin adducts by cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Linear dichroism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Modulation of platinum antitumor drug binding to DNA by linked and free intercalators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

12 July 2018

Metal complexes as DNA intercalators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

ERCC1 protein expression predicts the response of cisplatin-based neoadjuvant chemotherapy in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Duplex-promoted platination of adenine-N3 in the minor groove of DNA: challenging a longstanding bioinorganic paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Tuning the DNA reactivity of cis-platinum: conjugation to a mismatch-specific metallointercalator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Two mutations of basic residues within the N-terminus of HMG-1 B domain with different effects on DNA supercoiling and binding to bent DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

The influence of salts andpH on polarographic currents produced by denatured DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185219

26 September 2018

Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA interactions of cisplatin tethered to the DNA minor groove binder distamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA conformational change produced by the site-specific interstrand cross-link of trans-diamminedichloroplatinum(II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA bending by the chromosomal protein HMG1 and its high mobility group box domains. Effect of flanking sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of nucleic acids with electrically charged surfaces. II. Conformational changes in double-helical polynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarographic studies on the conformation of some platinum complexes: relations to anti-tumour activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of RNA Polymerase II Transcription in Human Cell Extracts by Cisplatin DNA Damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21806015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/MP200309X

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

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