(Q35346350)

7 August 2017

1 reference

title

Nonconventional chemical inhibitors of microRNA: therapeutic scope (English)

1 reference

7 August 2017

1 reference

3

Souvik Maiti

1 reference

7 August 2017

author name string

Gopal Gunanathan Jayaraj

series ordinal

1

1 reference

7 August 2017

Smita Nahar

series ordinal

2

1 reference

7 August 2017

language of work or name

English

0 references

publication date

20 October 2014

1 reference

7 August 2017

published in

Chemical Communications

1 reference

7 August 2017

volume

51

1 reference

7 August 2017

issue

5

1 reference

7 August 2017

page(s)

820-831

1 reference

Molecular biology. Glimpses of a tiny RNA world

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA function in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA functions in stress responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs in stress signaling and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A high-resolution structure of the pre-microRNA nuclear export machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Dicer recognizes the 5' end of RNA for efficient and accurate processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Biogenesis of small RNAs in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

An analysis of human microRNA and disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

miRCancer: a microRNA-cancer association database constructed by text mining on literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

miR2Disease: a manually curated database for microRNA deregulation in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

HMDD v2.0: a database for experimentally supported human microRNA and disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Cancer genes and the pathways they control

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Sequence-specific inhibition of small RNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Inhibition of microRNA function by antimiR oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Perspectives on chemistry and therapeutic applications of Locked Nucleic Acid (LNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

LNA-modified oligonucleotides mediate specific inhibition of microRNA function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Treatment of HCV infection by targeting microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Silencing of microRNA families by seed-targeting tiny LNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs as therapeutic targets in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA therapeutics in cardiovascular medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Target RNA-directed trimming and tailing of small silencing RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A general purpose RNA-cleaving DNA enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Antagomirzymes: oligonucleotide enzymes that specifically silence microRNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

“Locked onto the target”: increasing the efficiency of antagomirzymes using locked nucleic acid modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Antisense, RNAi, and gene silencing strategies for therapy: mission possible or impossible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

How were new medicines discovered?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

How many drug targets are there?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The terminal loop region controls microRNA processing by Drosha and Dicer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The role of the precursor structure in the biogenesis of microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Small molecule modifiers of the microRNA and RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Emergence of chemical biology approaches to the RNAi/miRNA pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Targeting microRNAs with small molecules: from dream to reality

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Recognition of duplex RNA by helix-threading peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Macrocyclic helix-threading peptides for targeting RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A homogenous assay for micro RNA maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A rapid assay for miRNA maturation by using unmodified pre-miRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A molecular-beacon-based screen for small molecule inhibitors of miRNA maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

A small molecule enhances RNA interference and promotes microRNA processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Small-molecule inhibitors of microrna miR-21 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Identification of small molecules that suppress microRNA function and reverse tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Small molecule inhibition of RISC loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Discovering ligands for a microRNA precursor with peptoid microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Identification of inhibitors of microRNA function from small molecule screens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Drug repositioning: identifying and developing new uses for existing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Sequence-based design of bioactive small molecules that target precursor microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

DOCK 6: combining techniques to model RNA-small molecule complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Anti-cancer therapeutic potential of quinazoline based small molecules via global upregulation of miRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

RNA as a drug target: chemical, modelling, and evolutionary tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNA signatures in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs in disease and potential therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Causes and consequences of microRNA dysregulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

MicroRNAs as novel players in skin development, homeostasis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

miRBase: annotating high confidence microRNAs using deep sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Landscape of transcription in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Molecular mechanisms of long noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Understanding the transcriptome through RNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The four dimensions of noncoding RNA conservation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Long noncoding RNAs and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

The noncoding RNA revolution-trashing old rules to forge new ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4CC04514A

21 January 2018

Identifiers

DOI

10.1039/C4CC04514A

1 reference

7 August 2017

1 reference