(Q35390952)

8 August 2017

HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). (English)

1 reference

2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl)chromen-4-one

8 August 2017

1 reference

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7-Hydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-(5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl)-5-methoxychromen-4-one

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2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)chromen-4-one

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2-(2,4-Dihydroxyphenyl)-3,7-dihydroxy-8-(5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl)-5-methoxy-2,3-dihydrochromen-4-one

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1 reference

SOPHORA FLAVESCENS ROOT

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Kushenol K

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(2S)-5,7-dihydroxy-2-(2-hydroxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-1-benzopyran-4-one

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5

Matthias Hamburger

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8 August 2017

Xinzhou Yang

1

1 reference

8 August 2017

Igor Baburin

series ordinal

2

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8 August 2017

Inken Plitzko

series ordinal

3

1 reference

8 August 2017

Steffen Hering

series ordinal

4

1 reference

8 August 2017

language of work or name

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5 January 2011

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full work available at URL

8 August 2017

https://europepmc.org/articles/pmc3196987?pdf=render

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19 March 2024

https://api.unpaywall.org/v2/10.1007/s11030-010-9297-7?email=unpaywall_01@example.com

published in

Molecular Diversity

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8 August 2017

15

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8 August 2017

2

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8 August 2017

361-372

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https://api.unpaywall.org/v2/10.1007/s11030-010-9297-7?email=unpaywall_01@example.com

8 August 2017

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19 March 2024

access restriction status

open access

1 reference

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1007/s11030-010-9297-7

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cites work

HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Anti-inflammatory and anti-arthritic activity of total flavonoids of the roots of Sophora flavescens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Neuroprotective effects of an alkaloid-free ethyl acetate extract from the root of Sophora flavescens Ait. against focal cerebral ischemia in rats

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

The subunit arrangement and assembly of ionotropic receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

GABA A receptor subtype selectivity underlying selective anxiolytic effect of baicalin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Benzodiazepines in epilepsy: pharmacology and pharmacokinetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

GABAA receptors as targets for novel anxiolytic drugs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Automated fast perfusion of Xenopus oocytes for drug screening

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Medicinal chemical properties of successful central nervous system drugs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

GABA-A receptors: a viable target for novel anxiolytics?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Pharmacological properties of GABAA receptors containing gamma1 subunits.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Benzodiazepines and anxiety disorders: a review for the practicing physician

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Development of effective therapeutics targeting the GABAA receptor: naturally occurring alternatives.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Antibacterial and antiandrogen flavonoids from Sophora flavescens.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Constituents of Chinese Crude Drug "Kushen"(the Root of Sophora flavescens AIT.). Isolation of Five New Flavonoids and Formononetin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196987

Analysis of the set of GABA(A) receptor genes in the human genome.

27 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Subunit composition, distribution and function of GABA(A) receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Modulation of ionotropic GABA receptors by natural products of plant origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Identification and isolation of the cyclooxygenase-2 inhibitory principle in Isatis tinctoria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

HPLC-based activity profiling of Salvia miltiorrhiza for MAO A and iNOS inhibitory activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Glycosidase inhibitory flavonoids from Sophora flavescens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Binding of flavonoids from Sophora flavescens to the rat uterine estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

GABA(A) receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Biflavones from Rhus species with affinity for the GABA(A)/benzodiazepine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11030-010-9297-7

Neuropharmacological evaluation of the putative anxiolytic effects of Passiflora edulis Sims, its sub-fractions and flavonoid constituents

21 January 2018

1 reference

12 December 2020

Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla

1 reference

12 December 2020

Neuroactive flavonoids: new ligands for the Benzodiazepine receptors

1 reference

12 December 2020

Studies on the Constituents of Sophora Species. IV. : Constituents of the Root of Sophora angustifolia SIEB. et ZUCC. (1)

1 reference

12 December 2020

BI-32169, a Bicyclic 19-Peptide with Strong Glucagon Receptor Antagonist Activity fromStreptomycessp.

1 reference

12 December 2020

Na+-glucose cotransporter (SGLT) inhibitory flavonoids from the roots of Sophora flavescens

1 reference

12 December 2020

High affinity of the naturally-occurring biflavonoid, amentoflavon, to brain benzodiazepine receptors in vitro

1 reference

12 December 2020

Studies on the Constituents of Sophora flavescens AIT. III

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/YAKUSHI1947.105.8_736

Studies on the Constituents of Sophora Species. V. Constituents of the Root of Sophora angustifolia SIEB. et ZUCC. (2)

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.19.2126

Identifiers

DOI

10.1007/S11030-010-9297-7

1 reference

8 August 2017

1 reference

8 August 2017

1 reference