(Q35425337)

English

In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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Chiara Campanella

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Chiara Campanella

11

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Roberto Würth

9

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Alessandra Ratto

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Alessandra Ratto

3

0 references

object named as

Aldo Pagano

14

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Stefano Thellung

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Stefano Thellung

2

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Federica Barbieri

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Federica Barbieri

1

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Antonio Daga

15

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object named as

Tullio Florio

17

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author name string

Elisa Carra

4

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Europe PubMed Central

PubMed publication ID

8 August 2017

Valeria Marini

5

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Europe PubMed Central

PubMed publication ID

8 August 2017

Carmen Fucile

6

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Adriana Bajetto

7

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Alessandra Pattarozzi

8

1 reference

Europe PubMed Central

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8 August 2017

Monica Gatti

10

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Europe PubMed Central

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8 August 2017

Guendalina Vito

12

1 reference

Europe PubMed Central

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8 August 2017

Francesca Mattioli

13

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8 August 2017

Angelo Ferrari

16

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8 August 2017

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7 April 2015

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Europe PubMed Central

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8 August 2017

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Europe PubMed Central

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8 August 2017

15

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Europe PubMed Central

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8 August 2017

228

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Europe PubMed Central

PubMed publication ID

8 August 2017

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Creative Commons Attribution 4.0 International

7 April 2015

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April 2022 Public Data File from Crossref

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Potential applications for biguanides in oncology

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Breast cancer stem cells

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Repositioning metformin for cancer prevention and treatment

1 reference

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1 reference

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Differential role of EGF and BFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensibility.

1 reference

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Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.

1 reference

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1 reference

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Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

1 reference

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Identification of triple-negative and basal-like canine mammary carcinomas using four basal markers.

1 reference

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Metformin is synthetically lethal with glucose withdrawal in cancer cells.

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Cancer stem cells: impact, heterogeneity, and uncertainty

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CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis.

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Canine tumors: a spontaneous animal model of human carcinogenesis

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Canine mammary tumours as a model to study human breast cancer: most recent findings.

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Dog models of naturally occurring cancer

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Metformin and cancer: new applications for an old drug

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Global cancer statistics

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Molecular biological aspects on canine and human mammary tumors

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The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells.

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Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

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Translation of new cancer treatments from pet dogs to humans

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Mammary stem cells and breast cancer--role of Notch signalling.

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27 July 2018

Practices and pitfalls of mouse cancer models in drug discovery.

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27 July 2018

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

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27 July 2018

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

1 reference

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27 July 2018

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

27 July 2018

Prospective identification of tumorigenic breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

27 July 2018

1 reference

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27 July 2018

Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

27 July 2018

Identification of tumor-initiating cells in a canine hepatocellular carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.

1 reference

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26 September 2018

Cancer stem cells: A contentious hypothesis now moving forward.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Immunodetection of cells with a CD44+/CD24- phenotype in canine mammary neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Unravelling cancer stem cell potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Isolation of stem-like cells from spontaneous feline mammary carcinomas: phenotypic characterization and tumorigenic potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Metformin: multi-faceted protection against cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

CD44 is associated with proliferation, rather than a specific cancer stem cell population, in cultured canine cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Isolation of canine mammary cells with stem cell properties and tumour-initiating potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Identification of cancer stem cells in dog glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Dose translation from animal to human studies revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Isolation and characterisation of cancer stem cells from canine osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

A prospective analysis of immunohistochemically determined estrogen receptor alpha and progesterone receptor expression and host and tumor factors as predictors of disease-free period in mammary tumors of the dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397725

26 September 2018

Targeting breast cancer stem cells

1 reference

https://api.crossref.org/works/10.1186%2FS12885-015-1235-8

21 January 2018

[Effect of phenformin on mammary gland tumor induction in rats]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of metformin by tissues of the normal and diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Goat anti-human GM-CSF recognizes canine GM-CSF

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR and microvessel density in canine malignant mammary tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12885-015-1235-8

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

Sitelinks

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