(Q53089167)

11 May 2018

title

Unravelling cancer stem cell potential. (English)

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11 May 2018

main subject

neoplastic stem cells

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2

Cédric Blanpain

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11 May 2018

author name string

Benjamin Beck

series ordinal

1

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11 May 2018

language of work or name

English

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publication date

1 October 2013

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11 May 2018

published in

Nature Reviews Cancer

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11 May 2018

volume

13

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11 May 2018

page(s)

727-738

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11 May 2018

issue

10

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11 May 2018

https://scigraph.springernature.com/pub.10.1038/nrc3597

exact match

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cites work

Stem cells and niches: mechanisms that promote stem cell maintenance throughout life

1 reference

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

31 March 2020

2 references

31 March 2020

12 December 2020

Permanent coverage of large burn wounds with autologous cultured human epithelium

1 reference

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

31 March 2020

1 reference

Tracing epithelial stem cells during development, homeostasis, and repair

31 March 2020

1 reference

Testicular teratomas. I. Demonstration of teratogenesis by metamorphosis of multipotential cells

31 March 2020

1 reference

Clonal evolution in cancer

31 March 2020

1 reference

Three clonal types of keratinocyte with different capacities for multiplication

31 March 2020

1 reference

Segregation of keratinocyte colony-forming cells in the bulge of the rat vibrissa

31 March 2020

1 reference

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

31 March 2020

1 reference

Morphogenesis and renewal of hair follicles from adult multipotent stem cells

31 March 2020

1 reference

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

31 March 2020

1 reference

Capturing and profiling adult hair follicle stem cells.

31 March 2020

1 reference

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

31 March 2020

1 reference

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

31 March 2020

1 reference

Eyes wide open: a critical review of sphere-formation as an assay for stem cells

31 March 2020

1 reference

EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells

31 March 2020

1 reference

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

31 March 2020

1 reference

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

31 March 2020

1 reference

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

31 March 2020

1 reference

Isolation and in vitro expansion of human colonic stem cells.

31 March 2020

1 reference

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

31 March 2020

1 reference

Identification of human brain tumour initiating cells

31 March 2020

1 reference

Identification and expansion of human colon-cancer-initiating cells

31 March 2020

1 reference

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

31 March 2020

1 reference

Prospective identification of tumorigenic prostate cancer stem cells

31 March 2020

1 reference

Identification and expansion of the tumorigenic lung cancer stem cell population

31 March 2020

1 reference

Identification and characterization of ovarian cancer-initiating cells from primary human tumors

31 March 2020

1 reference

Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma.

31 March 2020

1 reference

Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior.

31 March 2020

1 reference

Limiting factors in murine hematopoietic stem cell assays.

31 March 2020

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

31 March 2020

1 reference

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

31 March 2020

1 reference

Prospective identification of tumorigenic breast cancer cells

31 March 2020

1 reference

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

31 March 2020

1 reference

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

31 March 2020

1 reference

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

31 March 2020

1 reference

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

31 March 2020

1 reference

Identification of pancreatic cancer stem cells

31 March 2020

1 reference

Cancer stem cell definitions and terminology: the devil is in the details.

31 March 2020

1 reference

Tumor-initiating cells are rare in many human tumors

31 March 2020

1 reference

Efficient tumour formation by single human melanoma cells

31 March 2020

1 reference

Identification of cells initiating human melanomas

31 March 2020

1 reference

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

31 March 2020

1 reference

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

31 March 2020

1 reference

Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

31 March 2020

1 reference

Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness.

31 March 2020

1 reference

Genetic variegation of clonal architecture and propagating cells in leukaemia

31 March 2020

1 reference

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

31 March 2020

1 reference

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

31 March 2020

1 reference

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

31 March 2020

1 reference

Single-cell dissection of transcriptional heterogeneity in human colon tumors

31 March 2020

1 reference

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling

31 March 2020

1 reference

Primary tumor genotype is an important determinant in identification of lung cancer propagating cells

31 March 2020

1 reference

Tracing the cellular origin of cancer

31 March 2020

1 reference

Cells of origin in cancer

31 March 2020

1 reference

Identification of stem cells in small intestine and colon by marker gene Lgr5

31 March 2020

1 reference

Distinct contribution of stem and progenitor cells to epidermal maintenance.

31 March 2020

1 reference

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

31 March 2020

1 reference

A single type of progenitor cell maintains normal epidermis.

31 March 2020

1 reference

A single progenitor population switches behavior to maintain and repair esophageal epithelium

31 March 2020

1 reference

Defining the mode of tumour growth by clonal analysis

31 March 2020

1 reference

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

31 March 2020

1 reference

Crypt stem cells as the cells-of-origin of intestinal cancer

31 March 2020

1 reference

Bmi1 is expressed in vivo in intestinal stem cells

31 March 2020

1 reference

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

31 March 2020

1 reference

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

31 March 2020

1 reference

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

31 March 2020

1 reference

Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells

31 March 2020

1 reference

DCAMKL-1 expression identifies Tuft cells rather than stem cells in the adult mouse intestinal epithelium

31 March 2020

1 reference

Dclk1 distinguishes between tumor and normal stem cells in the intestine

31 March 2020

1 reference

Intravital imaging of cancer stem cell plasticity in mammary tumors

31 March 2020

1 reference

CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

31 March 2020

1 reference

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

31 March 2020

1 reference

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

31 March 2020

1 reference

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

31 March 2020

1 reference

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

31 March 2020

1 reference

Wnt signalling in stem cells and cancer

31 March 2020

1 reference

Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation

31 March 2020

1 reference

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling

31 March 2020

1 reference

A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer

31 March 2020

1 reference

Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice

31 March 2020

1 reference

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

31 March 2020

1 reference

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

31 March 2020

1 reference

Generation of a functional mammary gland from a single stem cell

31 March 2020

1 reference

Purification and unique properties of mammary epithelial stem cells

31 March 2020

1 reference

Distinct stem cells contribute to mammary gland development and maintenance

31 March 2020

1 reference

Isolation and functional characterization of murine prostate stem cells

31 March 2020

1 reference

Multipotent and unipotent progenitors contribute to prostate postnatal development

31 March 2020

1 reference

Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen.

31 March 2020

1 reference

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

31 March 2020

1 reference

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

31 March 2020

1 reference

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

31 March 2020

1 reference

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

31 March 2020

1 reference

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

31 March 2020

1 reference

The epithelial-mesenchymal transition generates cells with properties of stem cells

31 March 2020

1 reference

Clonal selection drives genetic divergence of metastatic medulloblastoma

31 March 2020

1 reference

Involvement of chemokine receptors in breast cancer metastasis

31 March 2020

1 reference

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

31 March 2020

1 reference

CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche

31 March 2020

1 reference

Halting metastasis through CXCR4 inhibition

31 March 2020

1 reference

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

31 March 2020

1 reference

A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer

31 March 2020

1 reference

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

31 March 2020

1 reference

Socializing with the neighbors: stem cells and their niche

31 March 2020

1 reference

Stem cells find their niche

31 March 2020

1 reference

Molecular mechanisms and clinical applications of angiogenesis

31 March 2020

1 reference

Vascular niche for adult hippocampal neurogenesis

31 March 2020

1 reference

Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells

31 March 2020

1 reference

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

31 March 2020

1 reference

A perivascular niche for brain tumor stem cells

31 March 2020

1 reference

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

31 March 2020

1 reference

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

31 March 2020

1 reference

The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis

31 March 2020

1 reference

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells

31 March 2020

1 reference

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

31 March 2020

1 reference

Modeling pO(2) distributions in the bone marrow hematopoietic compartment. I. Krogh's model

31 March 2020

1 reference

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

31 March 2020

1 reference

Hypoxia-inducible factors in physiology and medicine

31 March 2020

1 reference

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

31 March 2020

1 reference

Targeting HIF1α eliminates cancer stem cells in hematological malignancies.

31 March 2020

1 reference

HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells

31 March 2020

1 reference

Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

31 March 2020

1 reference

Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells.

31 March 2020

1 reference

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

31 March 2020

1 reference

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer

31 March 2020

1 reference

Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-α status

31 March 2020

1 reference

Functional regulation of HIF-1α under normoxia--is there more than post-translational regulation?

31 March 2020

1 reference

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

31 March 2020

1 reference

Interactions between cancer stem cells and their niche govern metastatic colonization

31 March 2020

1 reference

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

31 March 2020

1 reference

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

31 March 2020

1 reference

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

31 March 2020

1 reference

Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death

31 March 2020

1 reference

Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

31 March 2020

1 reference

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

31 March 2020

1 reference

Association of reactive oxygen species levels and radioresistance in cancer stem cells

31 March 2020

1 reference

Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

31 March 2020

1 reference

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

31 March 2020

1 reference

Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells

31 March 2020

1 reference

A restricted cell population propagates glioblastoma growth after chemotherapy

31 March 2020

1 reference

Cellular barcoding tool for clonal analysis in the hematopoietic system

31 March 2020

1 reference

Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding

31 March 2020

1 reference

Epithelial-mesenchymal transitions in development and disease

31 March 2020

1 reference

A dermal niche for multipotent adult skin-derived precursor cells.

31 March 2020

1 reference

Isolation of multipotent adult stem cells from the dermis of mammalian skin

31 March 2020

1 reference

FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer.

31 March 2020

1 reference

Generation of breast cancer stem cells through epithelial-mesenchymal transition

31 March 2020

1 reference

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

31 March 2020

1 reference

Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells

31 March 2020

1 reference

twist is required in head mesenchyme for cranial neural tube morphogenesis

31 March 2020

1 reference

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

31 March 2020

1 reference

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

31 March 2020

1 reference

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

31 March 2020

1 reference

Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition

31 March 2020

1 reference

Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation

31 March 2020

1 reference

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

31 March 2020

1 reference

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

31 March 2020

1 reference

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

31 March 2020

1 reference

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

31 March 2020

1 reference

The pattern of stem cell renewal in three epithelia. (esophagus, intestine and testis).

31 March 2020

1 reference

12 December 2020

The relationship between the spleen colony-forming cell and the haemopoietic stem cell

1 reference

12 December 2020

CD133 expression defines a tumor initiating cell population in primary human ovarian cancer

1 reference

12 December 2020

Teratocarcinogenic and tissue-forming potentials of the cell types comprising neoplastic embryoid bodies

1 reference

12 December 2020

Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3597

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11 May 2018

PubMed ID

24060864

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11 May 2018