(Q39312255)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22809961%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Metformin is synthetically lethal with glucose withdrawal in cancer cells (English)

1 reference

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8 February 2020

0 references

1 reference

1

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8 February 2020

Jorge Joven

5

1 reference

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8 February 2020

author name string

Cristina Oliveras-Ferraros

2

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8 February 2020

Sílvia Cufí

3

1 reference

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8 February 2020

Bruna Corominas-Faja

4

1 reference

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8 February 2020

Alejandro Vazquez-Martin

7

1 reference

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8 February 2020

Begoña Martin-Castillo

6

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8 February 2020

publication date

1 August 2012

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8 February 2020

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8 February 2020

volume

11

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8 February 2020

issue

15

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8 February 2020

page(s)

2782-2792

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Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena

8 February 2020

cites work

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Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells' tolerance to nutrient starvation

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21 January 2018

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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

21 January 2018

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The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling

21 January 2018

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The role of LKB1 and AMPK in cellular responses to stress and damage

21 January 2018

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Optical imaging of metabolism in HER2 overexpressing breast cancer cells

21 January 2018

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Changes in 2-fluoro-2-deoxy-D-glucose incorporation, hexokinase activity and lactate production by breast cancer cells responding to treatment with the anti-HER-2 antibody trastuzumab

21 January 2018

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Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells.

21 January 2018

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21 January 2018

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Metformin induces unique biological and molecular responses in triple negative breast cancer cells

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21 January 2018

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Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

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The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

21 January 2018

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Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

21 January 2018

1 reference

Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells.

21 January 2018

1 reference

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

21 January 2018

1 reference

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

21 January 2018

1 reference

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

21 January 2018

1 reference

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging

21 January 2018

1 reference

Energy metabolism plasticity enables stemness programs

21 January 2018

1 reference

Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

21 January 2018

1 reference

OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer

21 January 2018

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Radiation-induced reprogramming of breast cancer cells

21 January 2018

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Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells

21 January 2018

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Metformin lowers the threshold for stress-induced senescence: a role for the microRNA-200 family and miR-205.

21 January 2018

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Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo.

21 January 2018

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Dose translation from animal to human studies revisited

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A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases

21 January 2018

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Modern approach to metabolic rehabilitation of cancer patients: biguanides (phenformin and metformin) and beyond

21 January 2018

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Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy

21 January 2018

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Gerosuppressant metformin: less is more

21 January 2018

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Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer

21 January 2018

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Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture

21 January 2018

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Homologous recombination in cancer development, treatment and development of drug resistance.

21 January 2018

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Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

21 January 2018

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Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models

21 January 2018

1 reference

Metformin activates AMP kinase through inhibition of AMP deaminase

21 January 2018

1 reference

Metformin and reprogramming into iPSCs

21 January 2018

1 reference