(Q53184000)

12 May 2018

title

Metformin lowers the threshold for stress-induced senescence: a role for the microRNA-200 family and miR-205. (English)

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12 May 2018

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6

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12 May 2018

Jorge Joven

7

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12 May 2018

Joaquim Bosch-Barrera

8

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12 May 2018

Begoña Martin-Castillo

10

object named as

Begoña Martin-Castillo

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12 May 2018

Sílvia Cufí

1

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12 May 2018

Alejandro Vazquez-Martin

2

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12 May 2018

Cristina Oliveras-Ferraros

3

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12 May 2018

Rosa Quirantes

4

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12 May 2018

Antonio Segura-Carretero

5

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12 May 2018

Sonia Del Barco

9

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12 May 2018

Luciano Vellon

11

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12 May 2018

Javier A Menendez

12

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12 May 2018

publication date

15 March 2012

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12 May 2018

number of pages

12

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based on heuristic

inferred from page(s)

published in

Cell Cycle

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12 May 2018

volume

11

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12 May 2018

issue

6

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12 May 2018

page(s)

1235-1246

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12 May 2018

Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

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Cellular senescence as a tumor-protection mechanism: the essential role of counting

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Cellular senescence in vivo: a barrier to tumorigenesis

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The essence of senescence

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The DNA damage signaling pathway connects oncogenic stress to cellular senescence.

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Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

21 January 2018

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Jailbreak: oncogene-induced senescence and its evasion

21 January 2018

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Senescence and pre-malignancy: how do tumors progress?

21 January 2018

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Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence

21 January 2018

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Zeb1 links epithelial-mesenchymal transition and cellular senescence

21 January 2018

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Deregulating EMT and senescence: double impact by a single twist.

21 January 2018

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Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

21 January 2018

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EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

21 January 2018

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Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.

21 January 2018

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Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

What is the malignant nature of human ductal carcinoma in situ?

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Autophagy positively regulates the CD44(+) CD24(-/low) breast cancer stem-like phenotype

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Senescence induction; a possible cancer therapy

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Cellular senescence in the development and treatment of cancer.

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin

21 January 2018

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Cell cycle arrest is not senescence

21 January 2018

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Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin

21 January 2018

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions?

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection.

21 January 2018

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Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts

21 January 2018

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MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts

21 January 2018

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Differential expression of oncogenic miRNAs in proliferating and senescent human fibroblasts

21 January 2018

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Senescence-associated microRNAs linked to tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Hormesis: the dose-response revolution

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Hormetic mechanisms of anti-aging and rejuvenating effects of repeated mild heat stress on human fibroblasts in vitro.

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

21 January 2018

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Hormetic prevention of molecular damage during cellular aging of human skin fibroblasts and keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Hormesis [biological effects of low level exposures (BELLE)] and dermatology

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Hormesis, cell death and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Hormesis does not make sense except in the light of TOR-driven aging

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Cellular senescence: mitotic clock or culture shock?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Cellular life span and the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

A role for AMPK in increased insulin action after serum starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Mitochondrial rejuvenation after induced pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Energy metabolism in human pluripotent stem cells and their differentiated counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Empowering self-renewal and differentiation: the role of mitochondria in stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Stressed tumor cell, chemosensitized cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Cellular senescence controls fibrosis in wound healing

21 January 2018

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https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA-181a

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Generation of induced pluripotent stem cells in the absence of drug selection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

Elite and stochastic models for induced pluripotent stem cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19665

21 January 2018

Identifiers

DOI

10.4161/CC.11.6.19665

1 reference

12 May 2018

PubMed ID

22356767

1 reference

12 May 2018