(Q33284158)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Joan Brunet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

Alegria Carrasco-Pancorbo

30 December 2019

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Rocio Garcia Villalba

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

Alberto Fernández Gutiérrez

30 December 2019

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Antonio Segura Carretero

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Alejandro Vazquez-Martin

2

object named as

Alejandro Vazquez-Martin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Ramon Colomer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

9 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

80

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

30 December 2019

copyright license

start time

9 May 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2407-7-80

0 references

cites work

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HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail".

21 June 2018

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Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer.

21 June 2018

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21 June 2018

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Adjuvant trastuzumab therapy for HER2-overexpressing breast cancer: what we know and what we still need to learn

21 June 2018

1 reference

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Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

21 June 2018

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Mediterranean diet, olive oil and cancer.

21 June 2018

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Diet, cancer, and the lipidome

21 June 2018

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Scientific evidence of interventions using the Mediterranean diet: a systematic review

21 June 2018

1 reference

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Herceptin: mechanisms of action and resistance

21 June 2018

1 reference

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

21 June 2018

1 reference

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A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (

21 June 2018

1 reference

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Oleocanthal in olive oil: between myth and reality

21 June 2018

1 reference

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Mechanisms of trastuzumab resistance and their clinical implications.

21 June 2018

1 reference

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Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells

21 June 2018

1 reference

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Evaluation of the antioxidant capacity of individual phenolic compounds in virgin olive oil.

21 June 2018

1 reference

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International conference on the healthy effect of virgin olive oil.

21 June 2018

1 reference

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Exogenous supplementation with omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells

21 June 2018

1 reference

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ERBB receptors and cancer: the complexity of targeted inhibitors

21 June 2018

1 reference

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Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation.

21 June 2018

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Olive oil and modulation of cell signaling in disease prevention

21 June 2018

1 reference

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Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification

21 June 2018

1 reference

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Mediterranean diet, antioxidants and cancer: the need for randomized trials.

21 June 2018

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Mediterranean diet and cancer

21 June 2018

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P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.

21 June 2018

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HER-2-targeted therapy: lessons learned and future directions.

21 June 2018

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Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 June 2018

1 reference

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Biologic and therapeutic role of HER2 in cancer

21 June 2018

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Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment

21 June 2018

1 reference

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Major phenolic compounds in olive oil: metabolism and health effects.

21 June 2018

1 reference

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Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action

21 June 2018

1 reference

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The development and clinical use of trastuzumab (Herceptin).

21 June 2018

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Olive oil as a functional food: epidemiology and nutritional approaches

21 June 2018

1 reference

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Phenolics from olive oil and its waste products. Biological activities in in vitro and in vivo studies

21 June 2018

1 reference

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The role of antioxidants in the Mediterranean diet

21 June 2018

1 reference

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Antioxidant and other biological activities of phenols from olives and olive oil.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Mechanism of action of trastuzumab and scientific update

21 June 2018

1 reference

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Biology of HER2 and its importance in breast cancer

21 June 2018

1 reference

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The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence.

21 June 2018

1 reference

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The role of overexpressed HER2 in transformation

21 June 2018

1 reference

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Mechanism of action of anti-HER2 monoclonal antibodies

21 June 2018

1 reference

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The basic biology of HER2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells

21 June 2018

1 reference

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Untangling the ErbB signalling network

21 June 2018

1 reference

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Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancer

21 June 2018

1 reference

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The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer.

21 June 2018

1 reference

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Dietary intake and bioavailability of polyphenols

21 June 2018

1 reference

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The antioxidant/anticancer potential of phenolic compounds isolated from olive oil

21 June 2018

1 reference

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The ErbB signaling network: receptor heterodimerization in development and cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Olive oil phenolics are dose-dependently absorbed in humans

21 June 2018

1 reference

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Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin).

21 June 2018

1 reference

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Enzymatic activation of oleuropein: a protein crosslinker used as a chemical defense in the privet tree

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Antioxidant and other activities of phenolics in olives/olive oil, typical components of the Mediterranean diet

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Functional assay for HER-2/neu demonstrates active signalling in a minority of HER-2/neu-overexpressing invasive human breast tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Pharmacological analysis of the iridoid oleuropein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Humanization of an anti-p185HER2 antibody for human cancer therapy

21 June 2018

1 reference

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Main polyphenols in the bitter taste of virgin olive oil. Structural confirmation by on-line high-performance liquid chromatography electrospray ionization mass spectrometry

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Qualitative and semiquantitative analysis of phenolic compounds in extra virgin olive oils as a function of the ripening degree of olive fruits by different analytical techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Electrophoretic identification and quantitation of compounds in the polyphenolic fraction of extra-virgin olive oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-80

Active signaling by HER-2/neu in a subpopulation of HER-2/neu-overexpressing ductal carcinoma in situ: clinicopathological correlates.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1878493

Olive oil phenols are absorbed in humans

31 October 2018

1 reference

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The identification of flavonoids as glycosides in human plasma

31 October 2018

1 reference

12 December 2020

Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells

1 reference

12 December 2020

Immunotherapy with an extract of Olea europaea quantified in mass units. Evaluation of the safety and efficacy after one year of treatment

1 reference

12 December 2020

Natural medicine: a 'new frontier' in oncology?

1 reference

12 December 2020

Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients

1 reference

12 December 2020

Trastuzumab in the treatment of breast cancer

1 reference

12 December 2020

Free Radical-Scavenging Properties of Olive Oil Polyphenols

1 reference

12 December 2020

Olive oil: more than just oleic acid

1 reference

12 December 2020

Activation state-specific monoclonal antibody detects tyrosine phosphorylated p185neu/erbB-2 in a subset of human breast tumors overexpressing this receptor

1 reference

12 December 2020

Capillary electrophoresis-electrospray ionization-mass spectrometry method to determine the phenolic fraction of extra-virgin olive oil

1 reference

12 December 2020

Rapid quantification of the phenolic fraction of Spanish virgin olive oils by capillary electrophoresis with UV detection

1 reference

12 December 2020

Oleic acid suppresses overexpression of ERBB2 oncogene

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-7-80

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 December 2019

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-7-80

9 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17490486%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference