(Q35539020)

8 August 2017

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title

Effector lymphocytes in islet cell autoimmunity (English)

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8 August 2017

1 reference

10.1023/A:1025156413404

https://api.crossref.org/works/10.1023/A:1025156413404

12 March 2024

author name string

Pere Santamaria

series ordinal

1

1 reference

8 August 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14501178

12 March 2024

publication date

1 September 2003

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Reviews in Endocrine and Metabolic Disorders

8 August 2017

published in

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8 August 2017

volume

4

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8 August 2017

issue

3

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8 August 2017

page(s)

271-280

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https://scigraph.springernature.com/pub.10.1023/a:1025156413404

8 August 2017

exact match

0 references

cites work

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

12 December 2020

In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

1 reference

12 December 2020

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

1 reference

12 December 2020

Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.

1 reference

12 December 2020

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

1 reference

12 December 2020

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

1 reference

12 December 2020

Inhibition of death receptor signals by cellular FLIP

1 reference

12 December 2020

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

1 reference

12 December 2020

Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity

1 reference

12 December 2020

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

12 December 2020

SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma

1 reference

12 December 2020

IL-1 produced and released endogenously within human islets inhibits beta cell function

1 reference

12 December 2020

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

1 reference

12 December 2020

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

1 reference

12 December 2020

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

1 reference

12 December 2020

In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

1 reference

12 December 2020

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

1 reference

12 December 2020

Nitric oxide inhibits the transcription repressor Yin-Yang 1 binding activity at the silencer region of the Fas promoter: a pivotal role for nitric oxide in the up-regulation of Fas gene expression in human tumor cells

1 reference

12 December 2020

Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

1 reference

12 December 2020

Insulin-dependent diabetes mellitus

1 reference

12 December 2020

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

1 reference

12 December 2020

Fas ligand (CD95L) protects neurons against perforin-mediated T lymphocyte cytotoxicity

1 reference

12 December 2020

Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved

1 reference

12 December 2020

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

1 reference

12 December 2020

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

1 reference

12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

1 reference

12 December 2020

Mechanism of lymphocyte-mediated cytotoxicity

1 reference

12 December 2020

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

1 reference

12 December 2020

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

1 reference

12 December 2020

Peritoneal exudate lymphocyte and mixed lymphocyte culture hybridomas are cytolytic in the absence of cytotoxic cell proteinases and perforin

1 reference

12 December 2020

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

1 reference

12 December 2020

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

12 December 2020

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis.

1 reference

12 December 2020

Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes

1 reference

12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

12 December 2020

Monitoring gene expression of TNFR family members by beta-cells during development of autoimmune diabetes

1 reference

12 December 2020

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

1 reference

12 December 2020

Impaired binding of perforin on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells.

1 reference

12 December 2020

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

1 reference

12 December 2020

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

1 reference

12 December 2020

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

1 reference

12 December 2020

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

12 December 2020

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

1 reference

12 December 2020

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1 reference

12 December 2020

Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

1 reference

12 December 2020

Two CD95 (APO-1/Fas) signaling pathways

1 reference

12 December 2020

Evidence for a novel function of the CD40 ligand as a signalling molecule in T-lymphocytes

1 reference

12 December 2020

Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems

1 reference

12 December 2020

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

12 December 2020

Characterization of T Lymphocytes Infiltrating Human Pancreas Allograft Affected by Isletitis and Recurrent Diabetes

1 reference

12 December 2020

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

12 December 2020

Evidence that beta cell death in the nonobese diabetic mouse is Fas independent

1 reference

12 December 2020

IAP family proteins--suppressors of apoptosis

1 reference

12 December 2020

The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302

1 reference

12 December 2020

Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion

1 reference

12 December 2020

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

1 reference

12 December 2020

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1 reference

12 December 2020

Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus

1 reference

12 December 2020

Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.

1 reference

12 December 2020

The temporal importance of TNFalpha expression in the development of diabetes

1 reference

12 December 2020

Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinants

1 reference

12 December 2020

Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells

1 reference

12 December 2020

Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

1 reference

12 December 2020

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

1 reference

12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

12 December 2020

HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus

1 reference

12 December 2020

Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells

1 reference

12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

12 December 2020

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

1 reference

12 December 2020

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1 reference

12 December 2020

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

1 reference

12 December 2020

Caspase-independent cell killing by Fas-associated protein with death domain

1 reference

12 December 2020

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes

1 reference

12 December 2020

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity

1 reference

12 December 2020

Significant role for Fas in the pathogenesis of autoimmune diabetes.

1 reference

12 December 2020

CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells

1 reference

12 December 2020

Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

1 reference

12 December 2020

Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity

1 reference

12 December 2020

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

12 December 2020

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1 reference

12 December 2020

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

12 December 2020

Distinction between interleukin-1-induced necrosis and apoptosis of islet cells

1 reference

12 December 2020

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

1 reference

12 December 2020

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 reference

12 December 2020

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

1 reference

12 December 2020

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

1 reference

12 December 2020

Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice

1 reference

12 December 2020

Fas ligand-induced c-Jun kinase activation in lymphoid cells requires extensive receptor aggregation but is independent of DAXX, and Fas-mediated cell death does not involve DAXX, RIP, or RAIDD.

1 reference

12 December 2020

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

1 reference

12 December 2020

Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.

1 reference

12 December 2020

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

12 December 2020

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1 reference

12 December 2020

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

1 reference

12 December 2020

In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes

1 reference

12 December 2020

Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

1 reference

12 December 2020

Constitutive class I-restricted exogenous presentation of self antigens in vivo

1 reference

12 December 2020

Cross-presentation, dendritic cells, tolerance and immunity

1 reference

12 December 2020

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

1 reference

12 December 2020

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.

1 reference

12 December 2020

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

1 reference

12 December 2020

Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

1 reference

12 December 2020

Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus

1 reference

12 December 2020

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

1 reference

12 December 2020

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

12 December 2020

A distinct pathway of cell-mediated apoptosis initiated by granulysin

1 reference

12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

12 December 2020

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo

1 reference

12 December 2020

CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

1 reference

12 December 2020

Granulysin: a novel antimicrobial peptide of cytolytic T lymphocytes and natural killer cells

1 reference

12 December 2020

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

12 December 2020

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

12 December 2020

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

1 reference

12 December 2020

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

1 reference

12 December 2020

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

12 December 2020

Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide

1 reference

12 December 2020

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

1 reference

12 December 2020

Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus

1 reference

12 December 2020

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

1 reference

12 December 2020

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

1 reference

12 December 2020

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

12 December 2020

Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells

1 reference

12 December 2020

Mechanisms of beta cell death in diabetes: a minor role for CD95.

1 reference

12 December 2020

Human leukocyte antigen-A24 and -DQA1*0301 in Japanese insulin-dependent diabetes mellitus: independent contributions to susceptibility to the disease and additive contributions to acceleration of beta-cell destruction

1 reference

12 December 2020

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

1 reference

12 December 2020

CD8(+) T cell-mediated spontaneous diabetes in neonatal mice

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12 December 2020

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

1 reference

12 December 2020

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

12 December 2020

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

1 reference

12 December 2020

Pancreatic beta-cell damage mediated by beta-cell production of interleukin-1. A novel mechanism for virus-induced diabetes

1 reference

12 December 2020

Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules

1 reference

12 December 2020

Beta cell apoptosis in T cell-mediated autoimmune diabetes

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12 December 2020

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

12 December 2020

Collaboration of helper and cytotoxic T lymphocytes

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12 December 2020

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

1 reference

12 December 2020

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

12 December 2020

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

12 December 2020

Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease.

1 reference

12 December 2020

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

1 reference

12 December 2020

Mouse islet cell lysis mediated by interleukin-1-induced Fas.

1 reference

12 December 2020

Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

1 reference

12 December 2020

Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function

1 reference

12 December 2020

CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis

1 reference

12 December 2020

Partial activation of CD8+ T cells by a self-derived peptide

1 reference

12 December 2020

Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens

1 reference

12 December 2020

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

12 December 2020

The role of Fas in autoimmune diabetes

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12 December 2020

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1 reference

12 December 2020

How TRAIL kills cancer cells, but not normal cells

1 reference

12 December 2020

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

1 reference

12 December 2020

A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population. Childhood Diabetes in Finland (DiMe) Study Group

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1025156413404

1 reference

Dimensions Publication ID

8 August 2017

1035047717

0 references

1 reference