(Q35551178)

25714462

8 August 2017

title

Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-κB signaling and inflammation (English)

1 reference

8 August 2017

0 references

5

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4 June 2020

Anthony Orr

7

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4 June 2020

author name string

Jie Chen

1

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4 June 2020

Igor L Leskov

2

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4 June 2020

Arif Yurdagul

3

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4 June 2020

Bonnie Thiel

4

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4 June 2020

Karen Y Stokes

6

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4 June 2020

publication date

24 February 2015

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8 August 2017

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4 June 2020

volume

8

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4 June 2020

issue

365

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4 June 2020

page(s)

ra20

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describes a project that uses

4 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4413941/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A novel interaction between the SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1 engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility

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Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics

12 July 2018

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Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow

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12 July 2018

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12 July 2018

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PECAM-1: a multi-functional molecule in inflammation and vascular biology

12 July 2018

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Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK.

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Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Atypical mechanism of NF-kappaB activation during reoxygenation stress in microvascular endothelium: a role for tyrosine kinases

12 July 2018

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Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

12 July 2018

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Reoxygenating microvascular endothelium exhibits temporal dissociation of NF-kappaB and AP-1 activation

12 July 2018

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12 July 2018

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Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation

12 July 2018

1 reference

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Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.

12 July 2018

1 reference

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Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

12 July 2018

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Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress

12 July 2018

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Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

12 July 2018

1 reference

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Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

12 July 2018

1 reference

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A casein kinase I activity is constitutively associated with Nck.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Oxidant-sensitive and phosphorylation-dependent activation of NF-kappa B and AP-1 in endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Oncogenes, growth factors, and signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

The T cell receptor/CD3 complex and CD2 stimulate the tyrosine phosphorylation of indistinguishable patterns of polypeptides in the human T leukemic cell line Jurkat

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Fine tuning of the threshold of T cell selection by the Nck adapters.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Hypoxia/reoxygenation stimulates Ca2+-dependent ICAM-1 mRNA expression in human aortic endothelial cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413941

Alterations in the local myocardial motion pattern in patients suffering from pressure overload due to aortic stenosis.

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005648

Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane

21 January 2018

1 reference

12 December 2020

Oxidative stress induces NF-kappaB nuclear translocation without degradation of IkappaBalpha

1 reference

12 December 2020

Postischemic inflammation: a role for mast cells in intestine but not in skeletal muscle

1 reference

12 December 2020

Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells

1 reference

12 December 2020

Blockade of platelet endothelial cell adhesion molecule-1 (PECAM-1) protects against ischemia-reperfusion injury in muscle flaps at microcirculatory level

1 reference

12 December 2020

Ischemia-reperfusion induced microvascular responses in LDL-receptor -/- mice

1 reference

12 December 2020

10.1126/SCISIGNAL.2005648

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25714462%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25714462%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

25714462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25714462%20AND%20SRC:MED&resulttype=core&format=json