(Q37785105)

23 August 2017

title

Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases (English)

1 reference

23 August 2017

Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases (English)

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

0 references

Shruti Singh

1

1 reference

23 August 2017

Sonal Vrishni

2

1 reference

23 August 2017

Irfan Rahman

4

1 reference

23 August 2017

Poonam Kakkar

5

1 reference

23 August 2017

Brijesh K. Singh

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20815789

6 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20815789

6 July 2024

publication date

1 November 2010

1 reference

full work available at URL

23 August 2017

http://www.tandfonline.com/doi/pdf/10.3109/10715762.2010.507670

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

published in

Free Radical Research

1 reference

23 August 2017

volume

44

1 reference

23 August 2017

issue

11

1 reference

23 August 2017

page(s)

1267-1288

1 reference

Drug-induced oxidative stress in rat liver from a toxicogenomics perspective

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Free radicals, metals and antioxidants in oxidative stress-induced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Reactive oxygen species and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Metals, toxicity and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Free radicals and antioxidants in normal physiological functions and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Protein carbonylation in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative stress and cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative stress and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2-Keap1 defines a physiologically important stress response mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

kelch encodes a component of intercellular bridges in Drosophila egg chambers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

New modes of translational control in development, behavior, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Translational control of long-lasting synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nuclear import and export signals in control of Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of antioxidant response element-dependent induction of detoxifying enzyme synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Functional antioxidant responsive elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Transcriptional Regulation of the Heme Oxygenase-1 Gene Via the Stress Response Element Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Functional characterization of transcription regulators that interact with the electrophile response element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The world according to Maf

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Fos and Jun: the AP-1 connection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

An important role of Nrf2-ARE pathway in the cellular defense mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Quinone reductases multitasking in the metabolic world

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

21 January 2018

Glutathione transferases

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Glutathione S-transferase polymorphisms: cancer incidence and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The immunopathogenesis of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2, a multi-organ protector?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of gamma-glutamylcysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defenses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Environmental toxicity, redox signaling and lung inflammation: the role of glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The GI-GPx gene is a target for Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Identification, characterization, and crystal structure of the Omega class glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

DT-diaphorase and cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Iron metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Balancing acts: molecular control of mammalian iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Iron metabolism and the IRE/IRP regulatory system: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Excess capacity of the iron regulatory protein system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

DNA and mRNA elements with complementary responses to hemin, antioxidant inducers, and iron control ferritin-L expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Ferritin and the response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Modulation of heme oxygenase in tissue injury and its implication in protection against gastrointestinal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The heme-responsive element of the mouse heme oxygenase-1 gene is an extended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The transcription factor Nrf2 is a therapeutic target against brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Role of microglial redox balance in modulation of neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative stress hypothesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Expression of Nrf2 in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Mitochondrial function and parental sex effect in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Traumatic brain injury induces the activation of the Nrf2-ARE pathway in the lung in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Insulin stimulation of gamma-glutamylcysteine ligase catalytic subunit expression increases endothelial GSH during oxidative stress: influence of low glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Role of NRF2 in protection against hyperoxic lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Diminished immunoreactivity of gamma-glutamylcysteine synthetase in the airways of smokers' lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 protects against airway disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Dual roles of Nrf2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Converting redox signaling to apoptotic activities by stress-responsive regulators HSF1 and NRF2 in fenretinide treated cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Activation of Nrf2 in defense against cadmium-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Acetaminophen-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kappaB in mouse macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Curcumin protects retinal cells from light-and oxidant stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Antioxidant therapeutic advances in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Dietary Supplementation of Curcumin Enhances Antioxidant and Phase II Metabolizing Enzymes in ddY Male Mice: Possible Role in Protection against Chemical Carcinogenesis and Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Molecular basis for chemoprevention by sulforaphane: a comprehensive review.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Upregulation of heme oxygenase-1 by brazilin via the phosphatidylinositol 3-kinase/Akt and ERK pathways and its protective effect against oxidative injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Simvastatin activates Keap1/Nrf2 signaling in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The Nrf2-ARE cytoprotective pathway in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Nuclear factor (erythroid-derived 2)-like 2 regulates drug resistance in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2010.507670

A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding

21 January 2018

10

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

The GSTM1 genetic polymorphism in healthy Saudi Arabians and Filipinos, and Saudi Arabians with coronary atherosclerosis

6 July 2024

103

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)

6 July 2024

126

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors

6 July 2024

136

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

Alzheimer's disease

137

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease.

6 July 2024

138

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

Alzheimer's disease

143

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

The role of metals in the etiology of Alzheimer's disease.

6 July 2024

145

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders

6 July 2024

153

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway.

6 July 2024

156

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

Huntington's Disease

158

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

6 July 2024

162

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

The transcription factor NRF2 protects against pulmonary fibrosis

6 July 2024

173

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

The Nrf2 transcription factor contributes to the induction of alpha-class GST isoenzymes in liver of acute cadmium or manganese intoxicated rats: comparison with the toxic effect on NAD(P)H:quinone reductase

6 July 2024

200

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin

6 July 2024

220

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

Genetic Ablation of Transcription Repressor Bach1 Reduces Neural Tissue Damage and Improves Locomotor Function after Spinal Cord Injury in Mice

6 July 2024

225

1 reference

https://api.crossref.org/works/10.3109/10715762.2010.507670

6 July 2024

Identifiers

1 reference

23 August 2017

1 reference