(Q35561050)

8 August 2017

title

Convergence of melatonin and serotonin (5-HT) signaling at MT2/5-HT2C receptor heteromers (English)

1 reference

5-hydroxytryptamine receptor 2C

8 August 2017

main subject

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Vincent Prevot

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Maud Kamal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Florence Gbahou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jean-Luc Guillaume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Avais M Daulat

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Abla Benleulmi-Chaachoua

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Marine Luka

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Patty Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Dina Kalbasi Anaraki

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Marc Baroncini

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Clotilde Mannoury la Cour

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Mark J Millan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Philippe Delagrange

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ralf Jockers

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

13 March 2015

1 reference

Journal of Biological Chemistry

8 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

290

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

11537-11546

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

6 June 2020

cites work

1 reference

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Mode of action of agomelatine: synergy between melatonergic and 5-HT2C receptors.

27 July 2018

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Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects

27 July 2018

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The effectiveness of multi-target agents in schizophrenia and mood disorders: Relevance of receptor signature to clinical action

27 July 2018

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Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

27 July 2018

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Improved donor/acceptor BRET couples for monitoring beta-arrestin recruitment to G protein-coupled receptors

27 July 2018

1 reference

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G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

27 July 2018

1 reference

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Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions

27 July 2018

1 reference

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Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

27 July 2018

1 reference

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

27 July 2018

1 reference

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Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application

27 July 2018

1 reference

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Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease.

27 July 2018

1 reference

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RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Activation of the Leptin Receptor by a Ligand-induced Conformational Change of Constitutive Receptor Dimers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Melatonin analogues as agonists and antagonists in the circadian system and other brain areas.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

The PDZ protein mupp1 promotes Gi coupling and signaling of the Mt1 melatonin receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Constitutive dimerization of human serotonin 5-HT4 receptors in living cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

New selective ligands of human cloned melatonin MT1 and MT2 receptors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Dual coupling of MT(1) and MT(2) melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Melatonin inhibits in vitro serotonergic phase shifts of the suprachiasmatic circadian clock

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Desensitization of the beta-adrenergic response in human brown adipocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416857

Differential signaling of human Mel1a and Mel1b melatonin receptors through the cyclic guanosine 3'-5'-monophosphate pathway

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25770211

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.559542

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770211%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference