(Q35568549)

8 August 2017

Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy (English)

1 reference

8 August 2017

0 references

14

Alain Fischer

0 references

Marina Cavazzana

13

Marina Cavazzana-Calvo

0 references

Salima Hacein-Bey-Abina

12

Salima Hacein-Bey-Abina

0 references

Christof von Kalle

27

Christof von Kalle

0 references

Martijn Brugman

Martijn H Brugman

2

0 references

Barbara Cassani

Barbara Cassani

21

0 references

Cynthia E. Dunbar

Cynthia E Dunbar

23

0 references

Alessandro Aiuti

Alessandro Aiuti

22

0 references

Fulvio Mavilio

Fulvio Mavilio

20

0 references

Adrian Thrasher

Adrian J Thrasher

26

0 references

Claudia Cattoglio

19

Claudia Cattoglio

1 reference

8 August 2017

28

Manfred Schmidt

1 reference

8 August 2017

Monique M A Verstegen

5

Monique M A Verstegen

1 reference

8 August 2017

29

Gerard Wagemaker

1 reference

8 August 2017

25

H Bobby Gaspar

1 reference

8 August 2017

1

Annette Deichmann

1 reference

8 August 2017

Cynthia C Bartholomae

3

Cynthia C Bartholomae

1 reference

8 August 2017

Kerstin Schwarzwaelder

4

Kerstin Schwarzwaelder

1 reference

8 August 2017

17

Hanno Glimm

1 reference

8 August 2017

18

Ulrich Abel

1 reference

8 August 2017

10

Reinhard Seger

1 reference

8 August 2017

Steven J Howe

6

1 reference

8 August 2017

Anne Arens

7

1 reference

8 August 2017

Marion G Ott

8

1 reference

8 August 2017

Dieter Hoelzer

9

1 reference

8 August 2017

Manuel Grez

11

1 reference

8 August 2017

Anna Paruzynski

15

1 reference

8 August 2017

Richard Gabriel

16

1 reference

8 August 2017

Christopher Baum

24

1 reference

8 August 2017

23 August 2011

1 reference

8 August 2017

1 reference

8 August 2017

19

1 reference

8 August 2017

11

1 reference

8 August 2017

2031-2039

1 reference

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

8 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Stem-cell gene therapy for the Wiskott-Aldrich syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Efficacy of gene therapy for X-linked severe combined immunodeficiency

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Transcription factor binding sites are genetic determinants of retroviral integration in the human genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Parallel tagged sequencing on the 454 platform

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Insertional mutagenesis and clonal dominance: biological and statistical considerations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Retroviral integration and human gene therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Real-time definition of non-randomness in the distribution of genomic events

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Hot spots of retroviral integration in human CD34+ hematopoietic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

IDconverter and IDClight: conversion and annotation of gene and protein IDs.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Gene therapy: therapeutic gene causing lymphoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Genome sequencing in microfabricated high-density picolitre reactors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

A census of human cancer genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Detection of functional DNA motifs via statistical over-representation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

RTCGD: retroviral tagged cancer gene database

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

DAVID: Database for Annotation, Visualization, and Integrated Discovery

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

MatchMiner: a tool for batch navigation among gene and gene product identifiers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Side effects of retroviral gene transfer into hematopoietic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Retroviral integration site analysis in hematopoietic stem cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222531

Redefining the common insertion site

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21862999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Murine leukemia induced by retroviral gene marking

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21862999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2011.178

1 reference

release_zxr3vguphfh3fjqpeg63yslcee

8 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zxr3vguphfh3fjqpeg63yslcee

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3222531

1 reference

8 August 2017

1 reference