(Q35568845)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

ChEBI release 2020-05-28

1 reference

1

1 reference

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22 December 2019

Qiao Li

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

2

Feras M Ghazawi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

Wafae Bakkar

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

publication date

11 December 2006

1 reference

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22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

page(s)

71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/1476-4598-5-71

22 December 2019

exact match

0 references

cites work

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Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity

12 July 2018

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Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species

12 July 2018

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12 July 2018

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B56 regulatory subunit of protein phosphatase 2A mediates valproic acid-induced p300 degradation

12 July 2018

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The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress

12 July 2018

1 reference

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Role of Akt/protein kinase B in the activity of transcriptional coactivator p300.

12 July 2018

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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

12 July 2018

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Akt as a mediator of cell death

12 July 2018

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12 July 2018

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Valproate: past, present, and future.

12 July 2018

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Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

12 July 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

12 July 2018

1 reference

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Worms gang up on bacteria

12 July 2018

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HeLa cells 50 years on: the good, the bad and the ugly

12 July 2018

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The protein kinase B/Akt signalling pathway in human malignancy

12 July 2018

1 reference

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Ten years of protein kinase B signalling: a hard Akt to follow

12 July 2018

1 reference

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AKT plays a central role in tumorigenesis

12 July 2018

1 reference

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

12 July 2018

1 reference

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Akt regulates cell survival and apoptosis at a postmitochondrial level

12 July 2018

1 reference

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Acetylation: a regulatory modification to rival phosphorylation?

12 July 2018

1 reference

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Cellular survival: a play in three Akts

12 July 2018

1 reference

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

12 July 2018

1 reference

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p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption

12 July 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

12 July 2018

1 reference

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

12 July 2018

1 reference

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

12 July 2018

1 reference

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Induction of NF-kappaB by the Akt/PKB kinase

12 July 2018

1 reference

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Modification of Chromatin Structure by the Thyroid Hormone Receptor

12 July 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

12 July 2018

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Regulation of cell death protease caspase-9 by phosphorylation

12 July 2018

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Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo

12 July 2018

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Structural and functional features of a specific nucleosome containing a recognition element for the thyroid hormone receptor.

12 July 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

12 July 2018

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12 July 2018

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

12 July 2018

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

12 July 2018

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Versatile molecular glue. Transcriptional control

12 July 2018

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Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Accessibility of a glucocorticoid response element in a nucleosome depends on its rotational positioning

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Studies on a New Human Cell Line (SiHa) Derived from Carcinoma of Uterus. I. Its Establishment and Morphology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl-positive human acute leukemia cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1762018

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

26 September 2018

1 reference

12 December 2020

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

1 reference

12 December 2020

Translational positioning of a nucleosomal glucocorticoid response element modulates glucocorticoid receptor affinity

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12 December 2020

The fundamental role of epigenetic events in cancer

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-4598-5-71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17156483%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference