(Q35569960)

English

Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance

scientific article published on 5 May 2015

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance (English)

1 reference

Europe PubMed Central

8 August 2017

Entamoeba histolytica

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drug resistance

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Kumiko Nakada-Tsukui

2

object named as

Kumiko Nakada-Tsukui

1 reference

Europe PubMed Central

8 August 2017

author name string

Gil M Penuliar

1

1 reference

Europe PubMed Central

8 August 2017

Tomoyoshi Nozaki

3

1 reference

Europe PubMed Central

8 August 2017

language of work or name

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publication date

5 May 2015

1 reference

Europe PubMed Central

8 August 2017

Frontiers in Microbiology

1 reference

Europe PubMed Central

8 August 2017

6

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Europe PubMed Central

8 August 2017

354

1 reference

Europe PubMed Central

8 August 2017

Regulation of virulence of Entamoeba histolytica

1 reference

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Ligand heterogeneity of the cysteine protease binding protein family in the parasitic protist Entamoeba histolytica

1 reference

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Efficacy of 5-nitroimidazoles for the treatment of giardiasis: a systematic review of randomized controlled trials

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Transcriptome analysis of encystation in Entamoeba invadens

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Cysteine protease-binding protein family 6 mediates the trafficking of amylases to phagosomes in the enteric protozoan Entamoeba histolytica

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Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolytica

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A metronidazole-resistant isolate of Blastocystis spp. is susceptible to nitric oxide and downregulates intestinal epithelial inducible nitric oxide synthase by a novel parasite survival mechanism

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Impaired parasite attachment as fitness cost of metronidazole resistance in Giardia lamblia

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1 reference

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Mechanism of trifluoromethionine resistance in Entamoeba histolytica.

1 reference

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Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica

1 reference

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1 reference

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A rapid, high-throughput viability assay for Blastocystis spp. reveals metronidazole resistance and extensive subtype-dependent variations in drug susceptibilities

1 reference

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Evidence for a novel Entamoeba histolytica lectin activity that recognises carbohydrates present on ovalbumin

1 reference

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The Generalization of `Student's' Problem when Several Different Population Variances are Involved

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Antibiotic resistance and its cost: is it possible to reverse resistance?

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Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship

1 reference

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Differences in the transcriptome signatures of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties

1 reference

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Metronidazole is still the drug of choice for treatment of anaerobic infections

1 reference

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Entamoeba histolytica: response of the parasite to metronidazole challenge on the levels of mRNA and protein expression.

1 reference

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Entamoeba histolytica modulates a complex repertoire of novel genes in response to oxidative and nitrosative stresses: implications for amebic pathogenesis.

1 reference

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Metronidazole resistance in Clostridium difficile is heterogeneous

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Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole

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Structure and content of the Entamoeba histolytica genome

1 reference

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Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase

1 reference

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The Entamoeba histolytica genome: primary structure and expression of proteolytic enzymes

1 reference

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1 reference

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Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome

1 reference

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1 reference

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1 reference

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1 reference

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In vitro resistance of Neisseria gonorrhoeae to metronidazole

1 reference

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The genome of the protist parasite Entamoeba histolytica

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Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans.

1 reference

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Flagyl (metronidazole).

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Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis

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The leucine-rich repeat as a protein recognition motif

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Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene

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Aggressive and defensive roles for chitinases.

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Two major 'higher molecular mass proteinases' of Entamoeba histolytica are identified as cysteine proteinases 1 and 2.

1 reference

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12 July 2018

Metronidazole resistance in the protozoan parasite Entamoeba histolytica is associated with increased expression of iron-containing superoxide dismutase and peroxiredoxin and decreased expression of ferredoxin 1 and flavin reductase

1 reference

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Three metronidazole-resistant strains of Trichomonas vaginalis from the United States.

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12 July 2018

Metabolism and metronidazole uptake in Trichomonas vaginalis isolates with different metronidazole susceptibilities

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12 July 2018

Viruses of Entamoeba histolytica. I. Identification of transmissible virus-like agents

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12 July 2018

Ferredoxin-dependent reduction of nitroimidazole derivatives in drug-resistant and susceptible strains of Trichomonas vaginalis.

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12 July 2018

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12 July 2018

Recurrence of hepatic amebiasis after successful treatment with metronidazole

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12 July 2018

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12 July 2018

Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis

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12 July 2018

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12 July 2018

Failure of metronidazole in a patient with hepatic amebic abscess

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12 July 2018

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12 July 2018

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12 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

Drug resistance and Giardia.

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26 September 2018

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26 September 2018

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26 September 2018

Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419850

26 September 2018

Overexpression of aldose reductase in liver cancers may contribute to drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419850

26 September 2018

Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419850

26 September 2018

Metronidazole uptake by sensitive and resistant isolates of Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419850

26 September 2018

Redox potential and oxygen concentration as factors in the susceptibility of Helicobacter pylori to nitroheterocyclic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419850

26 September 2018

Transcriptional and functional analysis of trifluoromethionine resistance in Entamoeba histolytica

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two cysteine protease inhibitors, EhICP1 and 2, localized in distinct compartments, negatively regulate secretion in Entamoeba histolytica

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metronidazole concentrations in human plasma, saliva, and gingival crevice fluid after a single dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WHO/PAHO/UNESCO report. A consultation with experts on amoebiasis. Mexico City, Mexico 28-29 January, 1997

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tritrichomonas foetus: stable anaerobic resistance to metronidazole in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of superoxide dismutase and pyruvate:ferredoxin oxidoreductase in mechanisms of metronidazole resistance in Entamoeba histolytica

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro Entamoeba histolytica adhesion to human endothelium: a comparison using two strains of different virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25999919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FMICB.2015.00354

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

ResearchGate publication ID

0 references

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