(Q35571585)

8 August 2017

1 reference

title

Effects of exogenous melatonin--a review (English)

1 reference

8 August 2017

Effects of Exogenous Melatonin—A Review (English)

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

26 March 2024

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

26 March 2024

author name string

Vladimir N. Anisimov

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585727

26 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

full work available at URL

8 August 2017

http://journals.sagepub.com/doi/pdf/10.1080/01926230390257885

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

26 March 2024

published in

Toxicologic Pathology

1 reference

8 August 2017

volume

31

1 reference

8 August 2017

issue

6

1 reference

8 August 2017

page(s)

589-603

1 reference

Life span extension and cancer risk: myths and reality

8 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The relationship between aging and carcinogenesis: a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Inhibitory effect of melatonin on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis of the uterine cervix and vagina in mice and mutagenesis in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin: A chronobiotic with anti-aging properties?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin stimulates brain glutathione peroxidase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Lack of melatonin effects on insulin action in normal rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

In the rat, exogenous melatonin increases the amplitude of pineal melatonin secretion by a direct action on the circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin protects neurons from singlet oxygen-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effects of pinealectomy and exogenous melatonin on serum leptin levels in male rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Evaluation of gene expression in human lymphocytes activated in the presence of melatonin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Role of the pineal gland and melatonin in the development of autoimmune diabetes in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin rhythms in mice: role in autoimmune and lymphoproliferative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin and mammary pathological growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Re-evaluation of the molecular pharmacology of mitomycin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The reductive hotspot hypothesis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Is human aging still mysterious enough to be left only to scientists?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Antiaging technology and pseudoscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Timing requirements for insulin/IGF-1 signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

In vivo and in situ action of melatonin on insulin secretion and some metabolic implications in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin biosynthesis in Drosophila: its nature and its effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin is a scavenger of peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin-immune system relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Does oxidative damage to DNA increase with age?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Free-radical theory of aging. Increasing the functional life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The molecular basis and clinical aspects of Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Isolation and characterization of an arylalkylamine N-acetyltransferase from Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Inhibitory effects of low doses of melatonin on induction of preneoplastic liver lesions in a medium-term liver bioassay in F344 rats: relation to the influence of electromagnetic near field exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Circadian rhythms of melatonin-synthesizing enzyme activities and melatonin levels in planarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Carcinogen-induced, free radical-mediated reduction in microsomal membrane fluidity: reversal by indole-3-propionic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

A conserved regulatory system for aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin increases gene expression for antioxidant enzymes in rat brain cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Proteolysis and the G1-S transition: the SCF connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Pineal cross-transplantation (old-to-young and vice versa) as evidence for an endogenous "aging clock".

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Sun-exposure- and aging-dependent p53 protein accumulation results in growth advantage for tumour cells in carcinogenesis of nonmelanocytic skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Is there a role for melatonin in supportive care?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Pineal indoles stimulate the gene expression of immunomodulating cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Transcriptional profile of aging in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Redox cycling of bleomycin-Fe(III) by an NADH-dependent enzyme, and DNA damage in isolated rat liver nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Long-term supplementation with melatonin delays reproductive senescence in rats, without an effect on number of primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Presence of links between zinc and melatonin during the circadian cycle in old mice: effects on thymic endocrine activity and on the survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effects of continuous light and melatonin treatment on energy metabolism of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Evidence of prooxidant and antioxidant action of melatonin on human liver cell line HepG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Pinealectomy-associated decrease in ribosomal gene activity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The chronobiotic properties of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin: a peroxyl radical scavenger more effective than vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Neuroimmunomodulation of aging. A program in the pineal gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin: a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Pineal control of aging: effect of melatonin and pineal grafting on aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Circadian melatonin and young-to-old pineal grafting postpone aging and maintain juvenile conditions of reproductive functions in mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Oxygen free radicals, melatonin, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effect of melatonin and pineal grafting on thymocyte apoptosis in aging mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Evidence for a direct effect of melatonin on mitochondrial genome expression of Siberian hamster brown adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The pineal gland and melatonin in relation to aging: a summary of the theories and of the data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin decreases mRNA for histone H4 in thymus of young rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels, and their responses to an inflammatory stimulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin blocks rat hippocampal neuronal apoptosis induced by amyloid beta-peptide 25-35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The programmed death phenomena, aging, and the Samurai law of biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Organisation of the circadian system in melatonin-proficient C3H and melatonin-deficient C57BL mice: a comparative investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin, a suppressor of spontaneous murine mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Neuroprotection by melatonin against ischemic neuronal injury associated with modulation of DNA damage and repair in the rat following a transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Human aging and melatonin. Clinical relevance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Modifications of circadian and circannual rhythms with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homologue chico.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Estimation of mutation frequencies in normal mammalian cells and the development of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin hype hard to swallow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Strain differences in susceptibility of female mice to 1,2-dimethylhydrazine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Cellular mechanisms of melatonin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Somatic mutations and aging: a re-evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Gene expression profiling of aging using DNA microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Prooxidant activity of melatonin promotes fas-induced cell death in human leukemic Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Effect of melatonin administration on qPer2, qPer3, and qClock gene expression in the suprachiasmatic nucleus of Japanese quail.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-beta immortalized pineal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230390257885

Purification, cloning, and characterization of a second arylalkylamine N-acetyltransferase from Drosophila melanogaster

21 January 2018

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Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats

26 March 2024

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Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats

26 March 2024

10

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Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes.

26 March 2024

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26 March 2024

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Antioxidative effects of melatonin in Drosophila melanogaster: antagonization of damage induced by the inhibition of catalase

26 March 2024

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The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat

26 March 2024

42

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https://api.crossref.org/works/10.1080/01926230390257885

Melatonin content of the pineal gland in different mouse strains

26 March 2024

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26 March 2024

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Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment

26 March 2024

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Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57BL/6 mice

26 March 2024

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https://api.crossref.org/works/10.1080/01926230390257885

The effect of pinealectomy on bodily growth, survival rate and P32 uptake in the rat.

26 March 2024

87

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https://api.crossref.org/works/10.1080/01926230390257885

Melatonin increases p53 and p21WAF1 expression in MCF-7 human breast cancer cells in vitro

26 March 2024

90

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https://api.crossref.org/works/10.1080/01926230390257885

5-aminolevulinate synthase mRNA levels in the Harderian gland of Syrian hamsters: correlation with porphyrin concentrations and regulation by androgens and melatonin

26 March 2024

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26 March 2024

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Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models

26 March 2024

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https://api.crossref.org/works/10.1080/01926230390257885

Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide.

26 March 2024

108

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

Melatonin regulates the respiratory burst of human neutrophils and their depolarization

26 March 2024

113

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

The pineal control of aging. The effects of melatonin and pineal grafting on the survival of older mice

26 March 2024

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26 March 2024

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https://api.crossref.org/works/10.1080/01926230390257885

Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum

26 March 2024

122

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https://api.crossref.org/works/10.1080/01926230390257885

Melatonin increases the intensity of respiratory burst and prevents L-selectin shedding in human neutrophils in vitro

26 March 2024

127

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

Augmentation of indices of oxidative damage in life-long melatonin-deficient rats

26 March 2024

130

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https://api.crossref.org/works/10.1080/01926230390257885

Dynamics of chromosomal aberrations in male mice of various strains during aging

26 March 2024

137

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The pineal neurohormone melatonin prevents in vivo and in vitro apoptosis in thymocytes

26 March 2024

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https://api.crossref.org/works/10.1080/01926230390257885

Melatonin regulates glucocorticoid receptor: an answer to its antiapoptotic action in thymus

26 March 2024

142

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https://api.crossref.org/works/10.1080/01926230390257885

The natural somatic mutation frequency and human carcinogenesis.

26 March 2024

145

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https://api.crossref.org/works/10.1080/01926230390257885

Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

26 March 2024

146

1 reference

https://api.crossref.org/works/10.1080/01926230390257885

Supplemental melatonin increases clonal lifespan in the protozoan Paramecium tetraurelia

26 March 2024

158

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Identifiers

1 reference

8 August 2017

1 reference