(Q35603140)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Effects of lysophospholipids on tumor microenvironment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Johannes Rolin

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

9 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

published in

Cancer Microenvironment

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

393-403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12307-011-0088-1

12 February 2020

exact match

0 references

cites work

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Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1 alpha from human mesenchymal stem cells

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Lysophosphatidic acid stimulates cell migration, invasion, and colony formation as well as tumorigenesis/metastasis of mouse ovarian cancer in immunocompetent mice

27 July 2018

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Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

27 July 2018

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Lysophosphatidic acid inhibits the cytotoxic activity of NK cells: involvement of Gs protein-mediated signaling.

27 July 2018

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The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer

27 July 2018

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27 July 2018

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Sphingosine-1-phosphate inhibits the cytotoxic activity of NK cells via Gs protein-mediated signalling

27 July 2018

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Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia

27 July 2018

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Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells

27 July 2018

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The alliance of sphingosine-1-phosphate and its receptors in immunity

27 July 2018

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Biological effects of lysophospholipids

27 July 2018

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Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

27 July 2018

1 reference

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Principles of bioactive lipid signalling: lessons from sphingolipids

27 July 2018

1 reference

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S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake

27 July 2018

1 reference

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Finding a way out: lymphocyte egress from lymphoid organs

27 July 2018

1 reference

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Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin

27 July 2018

1 reference

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Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology

27 July 2018

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Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.

27 July 2018

1 reference

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Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness.

27 July 2018

1 reference

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S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells

27 July 2018

1 reference

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Erythrocytes store and release sphingosine 1-phosphate in blood.

27 July 2018

1 reference

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Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses

27 July 2018

1 reference

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Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

27 July 2018

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Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

27 July 2018

1 reference

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Lysophospholipids as mediators of immunity

27 July 2018

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Antitumor activity of sphingosine kinase inhibitors

27 July 2018

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Sphingosine kinase: biochemical and cellular regulation and role in disease

27 July 2018

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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

27 July 2018

1 reference

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Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

27 July 2018

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Sphingosine kinase 1 is up-regulated in colon carcinogenesis

27 July 2018

1 reference

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Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720.

27 July 2018

1 reference

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Insights into seven and single transmembrane-spanning domain receptors and their signaling pathways in human natural killer cells.

27 July 2018

1 reference

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Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

27 July 2018

1 reference

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Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference

27 July 2018

1 reference

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Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization

27 July 2018

1 reference

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Physiological and pathological actions of sphingosine 1-phosphate.

27 July 2018

1 reference

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G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

27 July 2018

1 reference

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Lysophospholipids and chemokines activate distinct signal transduction pathways in T helper 1 and T helper 2 cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity.

27 July 2018

1 reference

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Discovery and evaluation of inhibitors of human sphingosine kinase

27 July 2018

1 reference

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Transduction of Multiple Effects of Sphingosine 1-Phosphate (S1P) on T Cell Functions by the S1P1 G Protein-Coupled Receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

The emerging role of lysophosphatidic acid in cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Lysophosphatidic acid induces human natural killer cell chemotaxis and intracellular calcium mobilization

27 July 2018

1 reference

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Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells

27 July 2018

1 reference

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Sphingolipids and the immune system

27 July 2018

1 reference

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Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1

27 July 2018

1 reference

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Lysophosphatidic acid is a bioactive mediator in ovarian cancer

27 July 2018

1 reference

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International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature

27 July 2018

1 reference

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

An oncogenic role of sphingosine kinase

27 July 2018

1 reference

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Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3

27 July 2018

1 reference

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Sphingosine 1-phosphate signalling in mammalian cells

27 July 2018

1 reference

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Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer

27 July 2018

1 reference

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Lysophosphatidic acid possesses dual action in cell proliferation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.

27 July 2018

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Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

21 January 2018

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Sphingosine 1-phosphate: synthesis and release

21 January 2018

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Lysophospholipids activate ovarian and breast cancer cells

21 January 2018

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Sphingosine-1-phosphate: signaling inside and out.

21 January 2018

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Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

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Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

21 January 2018

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Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells.

21 January 2018

1 reference

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Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.

21 January 2018

1 reference

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Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis

21 January 2018

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Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization

21 January 2018

1 reference

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Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity

21 January 2018

1 reference

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Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Aiming drug discovery at lysophosphatidic acid targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Lysophosphatidic acid signaling through LPA receptor subtype 1 induces colony scattering of gastrointestinal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1/3), COX-2, and NF-kappaB activation- and EGFR transactivation-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate mediate breast cancer cell biological functions through distinct mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Lysophospholipid growth factors and their G protein-coupled receptors in immunity, coronary artery disease, and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1.

21 January 2018

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Tipping the gatekeeper: S1P regulation of endothelial barrier function

21 January 2018

1 reference

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Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

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Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720.

21 January 2018

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Sphingosine 1-phosphate is a novel inhibitor of T-cell proliferation

21 January 2018

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The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

The influence of lysophosphatidic acid on the functions of human dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Modulation of natural killer cell cytotoxicity and cytokine release by the drug glatiramer acetate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

A novel laminin-induced LPA autocrine loop in the migration of ovarian cancer cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Chemokines activate natural killer cells through heterotrimeric G-proteins: implications for the treatment of AIDS and cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234328

Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion

25 September 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0088-1

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation

21 January 2018

1 reference

12 December 2020

p38 MAPK regulates group IIa phospholipase A2 expression in interleukin-1beta -stimulated rat neonatal cardiomyocytes

1 reference

12 December 2020

Metabolism and functional effects of sphingolipids in blood cells

1 reference

12 December 2020

Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers

1 reference

12 December 2020

IL-6 and IL-8 release is mediated via multiple signaling pathways after stimulating dendritic cells with lysophospholipids

1 reference

12 December 2020

Hypoxia Enhances Lysophosphatidic Acid Responsiveness in Ovarian Cancer Cells and Lysophosphatidic Acid Induces Ovarian Tumor MetastasisIn vivo

1 reference

12 December 2020

Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells

1 reference

12 December 2020

High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor

1 reference

12 December 2020

10.1007/S12307-011-0088-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904916%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21904916

1 reference