(Q35611443)

9 August 2017

title

Integrative omics analysis of rheumatoid arthritis identifies non-obvious therapeutic targets (English)

1 reference

9 August 2017

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1

John W Whitaker

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9 August 2017

6

Wei Wang

1 reference

9 August 2017

David L Boyle

2

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9 August 2017

Beatrix Bartok

3

1 reference

9 August 2017

Scott T Ball

4

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9 August 2017

Steffen Gay

5

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9 August 2017

Gary S Firestein

7

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9 August 2017

language of work or name

English

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publication date

22 April 2015

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9 August 2017

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9 August 2017

volume

10

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9 August 2017

issue

4

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9 August 2017

page(s)

e0124254

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

22 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4406750/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Integrative analysis of 111 reference human epigenomes

12 July 2018

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12 July 2018

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12 July 2018

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Prolonged tumor necrosis factor α primes fibroblast-like synoviocytes in a gene-specific manner by altering chromatin.

12 July 2018

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Network analysis identifies protein clusters of functional importance in juvenile idiopathic arthritis

12 July 2018

1 reference

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Essential role of Elmo1 in Dock2-dependent lymphocyte migration

12 July 2018

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

12 July 2018

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12 July 2018

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12 July 2018

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An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype

12 July 2018

1 reference

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Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis

12 July 2018

1 reference

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Regulation of DNA methylation in rheumatoid arthritis synoviocytes

12 July 2018

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Chromatin marks identify critical cell types for fine mapping complex trait variants

12 July 2018

1 reference

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Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

12 July 2018

1 reference

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DNA methylome signature in rheumatoid arthritis

12 July 2018

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Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

12 July 2018

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Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

12 July 2018

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Genome-scale analysis of aberrant DNA methylation in colorectal cancer

12 July 2018

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Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study

12 July 2018

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Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

12 July 2018

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Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria

12 July 2018

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Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo

12 July 2018

1 reference

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12 July 2018

1 reference

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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Acquisition, culture, and phenotyping of synovial fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Cadherin-11 in synovial lining formation and pathology in arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

DNA mismatch repair enzyme expression in synovial tissue

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Quantitative biomarker analysis of synovial gene expression by real-time PCR

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Evolving concepts of rheumatoid arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Tumour necrosis factor microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in Peruvian patients with rheumatoid arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Phosphoinositide 3-kinase δ regulates migration and invasion of synoviocytes in rheumatoid arthritis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

The GTPase Rac regulates the proliferation and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406750

Transcriptome analysis reveals specific changes in osteoarthritis synovial fibroblasts

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0124254

10.1371/JOURNAL.PONE.0124254

21 January 2018

Identifiers

DOI

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9 August 2017

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9 August 2017

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