(Q35680985)

9 August 2017

title

Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease (English)

1 reference

9 August 2017

Jackie L Johnson

1

1 reference

9 August 2017

Smitha Pillai

2

1 reference

9 August 2017

Danielle Pernazza

3

1 reference

9 August 2017

Saïd M Sebti

4

1 reference

9 August 2017

Nicholas J Lawrence

5

1 reference

9 August 2017

Srikumar P Chellappan

6

1 reference

9 August 2017

language of work or name

English

0 references

publication date

15 November 2011

1 reference

9 August 2017

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9 August 2017

volume

72

1 reference

9 August 2017

issue

2

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9 August 2017

page(s)

516-526

1 reference

Cyclin D as a therapeutic target in cancer

9 August 2017

cites work

1 reference

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Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine

27 July 2018

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Regulation of vascular endothelial growth factor receptors by Rb and E2F1: role of acetylation

27 July 2018

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Matrix metalloproteinases: regulators of the tumor microenvironment

27 July 2018

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E2F3 is a mediator of DNA damage-induced apoptosis

27 July 2018

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27 July 2018

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Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer

27 July 2018

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Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines

27 July 2018

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Disrupting the Rb-Raf-1 interaction: a potential therapeutic target for cancer

27 July 2018

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Mouse development with a single E2F activator.

27 July 2018

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A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

27 July 2018

1 reference

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The regulation of matrix metalloproteinases and their inhibitors.

27 July 2018

1 reference

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A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data--a case study using E2F1

27 July 2018

1 reference

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

27 July 2018

1 reference

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Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways

27 July 2018

1 reference

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Pocket proteins and cell cycle control

27 July 2018

1 reference

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Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

27 July 2018

1 reference

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The E2F family: specific functions and overlapping interests

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

The use of transient chromatin immunoprecipitation assays to test models for E2F1-specific transcriptional activation

27 July 2018

1 reference

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The retinoblastoma tumour suppressor in development and cancer

27 July 2018

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Gene expression changes in response to E2F1 activation.

27 July 2018

1 reference

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The identification of E2F1-specific target genes

27 July 2018

1 reference

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Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer

27 July 2018

1 reference

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Identification of novel E2F1-regulated genes by microarray

27 July 2018

1 reference

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Direct repression of the Mcl-1 promoter by E2F1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Use of chromatin immunoprecipitation to clone novel E2F target promoters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Matrix metalloproteinases in tumour invasion and metastasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Role of E2F in cell cycle control and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Transcriptional regulation of the dihydrofolate reductase gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

A rapid in vitro assay for quantitating the invasive potential of tumor cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Small molecule regulators of Rb-E2F pathway as modulators of transcription

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Chromatin immunoprecipitation assays: analyzing transcription factor binding and histone modifications in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Matrix metalloproteinases and the regulation of tissue remodelling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Principles of tumor suppression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

E2F-1 is essential for normal epidermal wound repair

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261351

Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22086850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-11-2647

1 reference

9 August 2017

1 reference

9 August 2017

1 reference