(Q38291801)

1 September 2017

Direct repression of the Mcl-1 promoter by E2F1. (English)

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1 September 2017

Rhonda Croxton

1

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1 September 2017

Yihong Ma

2

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1 September 2017

Lanxi Song

3

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1 September 2017

Eric B Haura

4

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1 September 2017

W Douglas Cress

5

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1 September 2017

language of work or name

English

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publication date

1 February 2002

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1 September 2017

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1 September 2017

21

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1 September 2017

1359-1369

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1 September 2017

9

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205157

1 September 2017

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cites work

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Adenovirus-mediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-3 accumulation is regulated by polypeptide stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Identification of E2F-3B, an alternative form of E2F-3 lacking a conserved N-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-1-induced p53-independent apoptosis in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F and the molecular mechanisms of early cell-cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Functional interplay between p53 and E2F through co-activator p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Role of the p53-homologue p73 in E2F1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Subunit composition determines E2F DNA-binding site specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Target gene specificity of E2F and pocket protein family members in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

E2F-1 functions in mice to promote apoptosis and suppress proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Apoptosis induction by E2F-1 via adenoviral-mediated gene transfer results in growth suppression of head and neck squamous cell carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205157

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205157

1 reference

Dimensions Publication ID

1 September 2017

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1 reference