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Regulation of skin aging and heart development by TAp63.
scientific article published on 9 December 2011
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Europe PubMed Central
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3263495
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18 January 2020
title
Regulation of skin aging and heart development by TAp63
(English)
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3263495
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18 January 2020
author
Matthieu Rouleau
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2
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18 January 2020
Michel Pucéat
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3263495
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18 January 2020
Daniel Aberdam
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M Paris
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18 January 2020
D Aberdam
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18 January 2020
publication date
9 December 2011
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Europe PubMed Central
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3263495
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18 January 2020
published in
Cell Death & Differentiation
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3263495
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18 January 2020
volume
19
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18 January 2020
issue
2
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18 January 2020
page(s)
186-193
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3263495
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retrieved
18 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cdd.2011.181
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Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.
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Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo
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Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells
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Identification and functional characterization of two new transcriptional variants of the human p63 gene
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Hes1 is expressed in the second heart field and is required for outflow tract development
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TAp63 prevents premature aging by promoting adult stem cell maintenance
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27 July 2018
Transcriptional network of p63 in human keratinocytes.
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Signaling pathways controlling second heart field development
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DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis
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DeltaNp63 is essential for epidermal commitment of embryonic stem cells.
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miR-203 represses 'stemness' by repressing DeltaNp63
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27 July 2018
A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes.
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27 July 2018
p63 Is essential for the proliferative potential of stem cells in stratified epithelia
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Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
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27 July 2018
p63 regulates proliferation and differentiation of developmentally mature keratinocytes
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An epidermal neural crest stem cell (EPI-NCSC) molecular signature
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p63 regulates an adhesion programme and cell survival in epithelial cells
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Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice
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An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer.
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p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
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27 July 2018
p63 is an essential proapoptotic protein during neural development
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27 July 2018
Regulation of the cyclin-dependent kinase inhibitor p57Kip2 expression by p63.
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27 July 2018
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart
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27 July 2018
p63 deficiency activates a program of cellular senescence and leads to accelerated aging
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Asymmetric cell divisions promote stratification and differentiation of mammalian skin
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27 July 2018
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria
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27 July 2018
Expression of different p63 variants in healing skin wounds suggests a role of p63 in reepithelialization and muscle repair
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27 July 2018
p63 is the molecular switch for initiation of an epithelial stratification program
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27 July 2018
Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans.
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27 July 2018
Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63
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27 July 2018
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27 July 2018
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
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27 July 2018
p63 is a p53 homologue required for limb and epidermal morphogenesis
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27 July 2018
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
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27 July 2018
Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27-->qter)].
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27 July 2018
TAp63 is important for cardiac differentiation of embryonic stem cells and heart development.
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25 September 2018
Directed differentiation of skin-derived precursors into functional vascular smooth muscle cells.
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25 September 2018
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25 September 2018
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25 September 2018
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25 September 2018
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25 September 2018
TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors.
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TAp63 induces senescence and suppresses tumorigenesis in vivo
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Age-dependent depletion of human skin-derived progenitor cells.
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25 September 2018
Identification of downstream genetic pathways of Tbx1 in the second heart field
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p63 protects the female germ line during meiotic arrest
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TAp63α mediates chemotherapeutic agent-induced apoptosis in human bone marrow mesenchymal stem cells
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Human hair follicles: "bulging" with neural crest-like stem cells
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12 December 2020
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SKP-ing TAp63: stem cell depletion, senescence, and premature aging
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12 December 2020
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R298Q mutation of p63 gene in autosomal dominant ectodermal dysplasia associated with arrhythmogenic right ventricular cardiomyopathy
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12 December 2020
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Dysregulation of TAp63 mRNA and protein levels in psoriasis
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12 December 2020
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Dilated cardiomyopathy in a 3-year-old girl with a terminal deletion, 46,XX,del(3)(q27-qter), of the long arm of chromosome 3
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12 December 2020
based on heuristic
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Identifiers
DOI
10.1038/CDD.2011.181
1 reference
stated in
Europe PubMed Central
PMC publication ID
3263495
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158419%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PMC publication ID
3263495
1 reference
stated in
Europe PubMed Central
PMC publication ID
3263495
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158419%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed publication ID
22158419
1 reference
stated in
Europe PubMed Central
PMC publication ID
3263495
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158419%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ResearchGate publication ID
51868399
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