(Q35713627)

English

Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.

scientific article published on 16 September 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

phosphorylation

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Junichi Nishimura

5

1 reference

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10 March 2020

13

object named as

Masaki Mori

1 reference

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10 March 2020

12

object named as

Yuichiro Doki

1 reference

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10 March 2020

Hirofumi Yamamoto

2

object named as

Hirofumi Yamamoto

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10 March 2020

14

object named as

Hideshi Ishii

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10 March 2020

4

object named as

Mamoru Uemura

1 reference

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10 March 2020

6

object named as

Taishi Hata

1 reference

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10 March 2020

Ichiro Takemasa

7

object named as

Ichiro Takemasa

1 reference

Europe PubMed Central

PMC publication ID

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10 March 2020

Tsunekazu Mizushima

8

object named as

Tsunekazu Mizushima

1 reference

Europe PubMed Central

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10 March 2020

Masamitsu Konno

3

object named as

Masamitsu Konno

1 reference

Europe PubMed Central

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10 March 2020

11

object named as

Jun Koseki

1 reference

Europe PubMed Central

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10 March 2020

Naohiro Nishida

9

object named as

Naohiro Nishida

1 reference

Europe PubMed Central

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10 March 2020

1

object named as

Atsushi Hamabe

1 reference

Europe PubMed Central

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10 March 2020

author name string

Koichi Kawamoto

10

1 reference

Europe PubMed Central

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10 March 2020

publication date

16 September 2014

1 reference

Europe PubMed Central

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10 March 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

105

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1100-1108

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Components of cancer metabolism and therapeutic interventions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

The seed and soil hypothesis revisited: current state of knowledge of inherited genes on prognosis in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Novel risk factors for lymph node metastasis in early invasive colorectal cancer: a multi-institution pathology review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Cancer metabolism: key players in metabolic reprogramming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Phosphofructokinase 1 glycosylation regulates cell growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Tumour budding: a promising parameter in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Redox regulation of cell migration and adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data directed for maximization of analytical reliability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

AACR centennial series: the biology of cancer metastasis: historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Tumor metabolism: cancer cells give and take lactate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Tumor cell metabolism: cancer's Achilles' heel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

In vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Risk factors for an adverse outcome in early invasive colorectal carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

On the Origin of Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Early role of Fsp1 in epithelial-mesenchymal transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

27 July 2018

Epigenetic modifications in colorectal cancer: molecular insights and therapeutic challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

C4.4A is associated with tumor budding and epithelial-mesenchymal transition of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4462394

25 September 2018

Colorectal cancer

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12487

21 January 2018

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12487

21 January 2018

Reproducibility Probability Score--incorporating measurement variability across laboratories for gene selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25060325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of glucose transporter-1, hexokinase-II, proliferating cell nuclear antigen and survival of patients with pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25060325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25060325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/CAS.12487

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25060325%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

ResearchGate publication ID

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