(Q35729405)

9 August 2017

title

The ins and outs of presenilin 1 membrane topology (English)

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9 August 2017

2

Randy Schekman

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9 August 2017

Jinoh Kim

1

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language of work or name

English

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publication date

19 January 2004

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

101

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9 August 2017

issue

4

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9 August 2017

page(s)

905-906

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The presenilins turned inside out: implications for their structures and functions

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Membrane proteins which exhibit multiple topological orientations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Membrane insertion and assembly of ductin: a polytopic channel with dual orientations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Genetic dissection of Alzheimer disease, a heterogeneous disorder

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327113

Reconstitution of gamma-secretase activity

12 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

Evidence for a six-transmembrane domain structure of presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

Membrane topology of the C. elegans SEL-12 presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

Protein topology of presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

Membrane topology of Alzheimer's disease-related presenilin 1. Evidence for the existence of a molecular species with a seven membrane-spanning and one membrane-embedded structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

Inversion of the membrane topology of SecG coupled with SecA-dependent preprotein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307297101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0307297101

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9 August 2017

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9 August 2017

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