(Q35738714)

10 August 2017

title

Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation (English)

1 reference

10 August 2017

Yong-Min Choi

1

1 reference

10 August 2017

Han-Kyul Kim

2

1 reference

10 August 2017

Wooyoung Shim

3

1 reference

10 August 2017

Muhammad Ayaz Anwar

4

1 reference

10 August 2017

Ji-Woong Kwon

5

1 reference

10 August 2017

Hyuk-Kwon Kwon

6

1 reference

10 August 2017

Hyung Joong Kim

7

1 reference

10 August 2017

Hyobin Jeong

8

1 reference

10 August 2017

Hwan Myung Kim

9

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10 August 2017

Daehee Hwang

10

1 reference

10 August 2017

Hyung Sik Kim

11

1 reference

10 August 2017

Sangdun Choi

12

1 reference

10 August 2017

language of work or name

English

0 references

publication date

6 August 2015

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10 August 2017

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10 August 2017

volume

10

1 reference

10 August 2017

issue

8

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10 August 2017

page(s)

e0135083

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Creative Commons Attribution 4.0 International

10 August 2017

copyright license

start time

6 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

Cytoscape

object named as

Cytoscape

2 references

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Mitochondrial modulation by Epigallocatechin 3-Gallate ameliorates cisplatin induced renal injury through decreasing oxidative/nitrative stress, inflammation and NF-kB in mice

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Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

12 July 2018

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In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells

12 July 2018

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Pro- and anti-apoptotic effects of p53 in cisplatin-treated human testicular cancer are cell context-dependent.

12 July 2018

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RRM2B suppresses activation of the oxidative stress pathway and is up-regulated by p53 during senescence

12 July 2018

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Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity

12 July 2018

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Carvedilol protects against apoptotic cell death induced by cisplatin in renal tubular epithelial cells

12 July 2018

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Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment

12 July 2018

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Mitaplatin increases sensitivity of tumor cells to cisplatin by inducing mitochondrial dysfunction.

12 July 2018

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Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

12 July 2018

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12 July 2018

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Reciprocal influence of the p53 and the hypoxic pathways

12 July 2018

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Real-time monitoring of cisplatin-induced cell death

12 July 2018

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EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes

12 July 2018

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Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

12 July 2018

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p53 regulation of metabolic pathways

12 July 2018

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Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity.

12 July 2018

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Hypoxia-induced alteration of mitochondrial genes in cardiomyocytes: role of Bnip3 and Pdk1.

12 July 2018

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A guided tour of the Trans-Proteomic Pipeline

12 July 2018

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STITCH 2: an interaction network database for small molecules and proteins

12 July 2018

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The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis

12 July 2018

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12 July 2018

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Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells

12 July 2018

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

12 July 2018

1 reference

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Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants

12 July 2018

1 reference

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Cisplatin-mediated impairment of mitochondrial DNA metabolism inversely correlates with glutathione levels

12 July 2018

1 reference

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ROS and p53: a versatile partnership

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

STITCH: interaction networks of chemicals and proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Computational methods for the comparative quantification of proteins in label-free LCn-MS experiments.

12 July 2018

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Flex-Hets differentially induce apoptosis in cancer over normal cells by directly targeting mitochondria

12 July 2018

1 reference

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Cisplatin cytotoxicity of auditory cells requires secretions of proinflammatory cytokines via activation of ERK and NF-kappaB.

12 July 2018

1 reference

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Chemically induced mouse models of intestinal inflammation

12 July 2018

1 reference

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Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity

12 July 2018

1 reference

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

12 July 2018

1 reference

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Preferential energy- and potential-dependent accumulation of cisplatin-gutathione complexes in human cancer cell lines (GLC4 and K562): A likely role of mitochondria.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Free radicals, metals and antioxidants in oxidative stress-induced cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

DAVID: Database for Annotation, Visualization, and Integrated Discovery

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Cellular response to oxidative stress: signaling for suicide and survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Systematic genetic analysis with ordered arrays of yeast deletion mutants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Endonuclease G is an apoptotic DNase when released from mitochondria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Application of antioxidants and other agents to prevent cisplatin ototoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Diagnosis and treatment of patients with testicular germ cell cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Dealing with energy demand: the AMP-activated protein kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Comparative aspects of propionate metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Comparison of label-free methods for quantifying human proteins by shotgun proteomics.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527592

Comparative analysis of caspase activation and apoptosis in renal tubular epithelial cells and renal cell carcinomas.

25 September 2018

1 reference

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Complex II Defect via Down-regulation of Iron-Sulfur Subunit Induces Mitochondrial Dysfunction and Cell Cycle Delay in Iron Chelation-induced Senescence-associated Growth Arrest

25 September 2018

1 reference

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Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta

25 September 2018

1 reference

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25 September 2018

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Crossref

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Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts

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Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

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Reactive oxygen species mediate p53 activation and apoptosis induced by sodium nitroprusside in SH-SY5Y cells

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Reduced glutathione protects against cisplatin-induced neurotoxicity in rats

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12 December 2020

10.1371/JOURNAL.PONE.0135083

Identifiers

DOI

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference