Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q40583911)
Watch
English
p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).
scientific article published on May 2004
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
title
p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1)
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
main subject
hypoxia
0 references
author
Tobias Schmid
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
Bernhard Brüne
series ordinal
4
object named as
Bernhard Brüne
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
author name string
Jie Zhou
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
Roman Köhl
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
language of work or name
English
0 references
publication date
1 May 2004
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
number of pages
7
1 reference
based on heuristic
inferred from page(s)
published in
Biochemical Journal
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
volume
380
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
page(s)
289-295
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
issue
Pt 1
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
cites work
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Regulation of angiogenesis by hypoxia: role of the HIF system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1alpha (HIF-1alpha).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Hypoxia-inducible factor and its biomedical relevance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
HIF-1 and tumor progression: pathophysiology and therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Hypoxia links ATR and p53 through replication arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
A conserved family of prolyl-4-hydroxylases that modify HIF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Signal transduction. How do cells sense oxygen?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Viral oncoproteins discriminate between p53 and the p53 homolog p73.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Recruitment of p300/CBP in p53-dependent signal pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Binding and modulation of p53 by p300/CBP coactivators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
An essential role for p300/CBP in the cellular response to hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
22 September 2017
Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
25 September 2017
Regulation of p53 mediated transactivation by the beta-subunit of protein kinase CK2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
25 September 2017
Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
25 September 2017
Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
17 June 2018
The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
20 August 2018
Three conformational states of the p300 CH1 domain define its functional properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
20 August 2018
Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
20 August 2018
Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
20 August 2018
Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224165
retrieved
20 August 2018
p53 inhibits hypoxia-inducible factor-stimulated transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14992692
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14992692
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14992692
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BJ20031299
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
PMCID
1224165
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
PubMed ID
14992692
1 reference
stated in
Europe PubMed Central
PMCID
1224165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14992692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
