(Q32065204)

6 July 2017

title

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation (English)

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6 July 2017

4

J Pouysségur

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author name string

E Berra

series ordinal

1

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6 July 2017

D E Richard

series ordinal

2

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6 July 2017

E Gothié

series ordinal

3

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6 July 2017

language of work or name

English

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publication date

1 February 2001

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6 July 2017

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6 July 2017

volume

491

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6 July 2017

issue

1-2

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6 July 2017

page(s)

85-90

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Purification and characterization of hypoxia-inducible factor 1

6 July 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902159-7

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 January 2021

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Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

7 January 2021

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

7 January 2021

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The hypoxic response: huffing and HIFing

7 January 2021

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Hypoxia-inducible factor 1: master regulator of O2 homeostasis

7 January 2021

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

7 January 2021

1 reference

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902159-7

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902159-7

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

7 January 2021

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 January 2021

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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

7 January 2021

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Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

7 January 2021

1 reference

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

7 January 2021

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The ubiquitin-proteasome pathway: on protein death and cell life

7 January 2021

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

7 January 2021

1 reference

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

7 January 2021

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Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1.

7 January 2021

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Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

7 January 2021

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Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

7 January 2021

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

7 January 2021

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

7 January 2021

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DNA damage induces phosphorylation of the amino terminus of p53

7 January 2021

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EPAS1 trans-activation during hypoxia requires p42/p44 MAPK

7 January 2021

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ERK activation upon hypoxia: involvement in HIF-1 activation

7 January 2021

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Mdm2 promotes the rapid degradation of p53

7 January 2021

1 reference

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Regulation of p53 stability by Mdm2

7 January 2021

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

7 January 2021

1 reference

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

7 January 2021

1 reference

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Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

7 January 2021

1 reference

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10.1016/S0014-5793(01)02159-7

7 January 2021

Identifiers

DOI

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6 July 2017

1 reference