(Q35740645)

10 August 2017

Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans (English)

1 reference

10 August 2017

Caenorhabditis elegans

0 references

response to nematicide

1 reference

Gene Ontology release 2020-05-02

3

1 reference

10 August 2017

Erik C Andersen

2

0 references

Leonid Kruglyak

series ordinal

5

object named as

Leonid Kruglyak

1 reference

10 August 2017

Rajarshi Ghosh

1

1 reference

PubMed ID

22301316

10 August 2017

Justin P Gerke

series ordinal

4

1 reference

PubMed ID

22301316

10 August 2017

language of work or name

English

0 references

publication date

1 February 2012

1 reference

10 August 2017

1 reference

10 August 2017

335

1 reference

10 August 2017

6068

1 reference

10 August 2017

574-578

1 reference

Principles of activation and permeation in an anion-selective Cys-loop receptor

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Natural allelic variation underlying a major fitness trade-off in Arabidopsis thaliana.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Recombinational landscape and population genomics of Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Widespread genetic incompatibility in C. elegans maintained by balancing selection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Population genetics of anthelmintic resistance in parasitic nematodes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

A novel approach for combining the use of in vitro and in vivo data to measure and detect emerging moxidectin resistance in gastrointestinal nematodes of goats.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Drug resistance in veterinary helminths

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Fitness costs of R-gene-mediated resistance in Arabidopsis thaliana.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

The genetics of ivermectin resistance in Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

An amino acid substitution in the pore region of a glutamate-gated chloride channel enables the coupling of ligand binding to channel gating.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

A nonparametric approach for mapping quantitative trait loci

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Statistical method for testing the neutral mutation hypothesis by DNA polymorphism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

Characterization of an extracellular serine protease of Leishmania (Leishmania) amazonensis.

12 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Efficacy of ivermectin in calves against a resistant Cooperia oncophora field isolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Mutations in the extracellular domains of glutamate-gated chloride channel alpha3 and beta subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Altered avr-14B gene transcription patterns in ivermectin-resistant isolates of the cattle parasites, Cooperia oncophora and Ostertagia ostertagi

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

R/qtl: QTL mapping in experimental crosses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Selection at linked sites shapes heritable phenotypic variation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

FusionDB: a database for in-depth analysis of prokaryotic gene fusion events

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Multiple sequence alignment with the Clustal series of programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Locating proteins in the cell using TargetP, SignalP and related tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Haploview: analysis and visualization of LD and haplotype maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

The structure of haplotype blocks in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

Efficient control of population structure in model organism association mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1214318

A point mutation in a glutamate-gated chloride channel confers abamectin resistance in the two-spotted spider mite, Tetranychus urticae Koch.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273849

25 September 2018

Identifiers

DOI

10.1126/SCIENCE.1214318

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PubMed ID

22301316