(Q35745442)

25878116

10 August 2017

title

Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes (English)

1 reference

10 August 2017

Daniel P Leaman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Michael B Zwick

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

15 April 2015

1 reference

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

6725-6745

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

9 June 2020

cites work

1 reference

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12 July 2018

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Transplanting supersites of HIV-1 vulnerability

12 July 2018

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Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

12 July 2018

1 reference

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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

12 July 2018

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12 July 2018

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

12 July 2018

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

12 July 2018

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Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

12 July 2018

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

12 July 2018

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Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates

12 July 2018

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12 July 2018

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Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers

12 July 2018

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12 July 2018

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12 July 2018

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Increased functional stability and homogeneity of viral envelope spikes through directed evolution

12 July 2018

1 reference

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Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate

12 July 2018

1 reference

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Proteolytic processing of the human immunodeficiency virus envelope glycoprotein precursor decreases conformational flexibility

12 July 2018

1 reference

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

12 July 2018

1 reference

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Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

12 July 2018

1 reference

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Anti-HIV B Cell lines as candidate vaccine biosensors

12 July 2018

1 reference

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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site

12 July 2018

1 reference

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Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Engineering, expression, purification, and characterization of stable clade A/B recombinant soluble heterotrimeric gp140 proteins

12 July 2018

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Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins

12 July 2018

1 reference

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Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

12 July 2018

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

12 July 2018

1 reference

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Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)

12 July 2018

1 reference

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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

12 July 2018

1 reference

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Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies

12 July 2018

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MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1.

12 July 2018

1 reference

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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

12 July 2018

1 reference

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Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

12 July 2018

1 reference

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Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

12 July 2018

1 reference

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Few and far between: how HIV may be evading antibody avidity

12 July 2018

1 reference

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Rational antibody-based HIV-1 vaccine design: current approaches and future directions

12 July 2018

1 reference

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The role of antibodies in HIV vaccines

12 July 2018

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In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1

12 July 2018

1 reference

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Immunogenicity of HIV-1 envelope glycoprotein oligomers

12 July 2018

1 reference

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The immune response during acute HIV-1 infection: clues for vaccine development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

12 July 2018

1 reference

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12 July 2018

1 reference

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Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies

12 July 2018

1 reference

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High-efficiency labeling of sialylated glycoproteins on living cells

12 July 2018

1 reference

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Biochemical and biophysical comparison of cleaved and uncleaved soluble, trimeric HIV-1 envelope glycoproteins

12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

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12 July 2018

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An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10

12 July 2018

1 reference

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Rational modifications of HIV-1 envelope glycoproteins for immunogen design

12 July 2018

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12 July 2018

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Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker

12 July 2018

1 reference

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Distribution and three-dimensional structure of AIDS virus envelope spikes

12 July 2018

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Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts

12 July 2018

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The HIV lipidome: a raft with an unusual composition

12 July 2018

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Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

12 July 2018

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Formaldehyde-treated, heat-inactivated virions with increased human immunodeficiency virus type 1 env can be used to induce high-titer neutralizing antibody responses

12 July 2018

1 reference

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

12 July 2018

1 reference

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Induction of humoral immune responses following vaccination with envelope-containing, formaldehyde-treated, thermally inactivated human immunodeficiency virus type 1.

12 July 2018

1 reference

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A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.

12 July 2018

1 reference

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Antibody neutralization and escape by HIV-1

12 July 2018

1 reference

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Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

12 July 2018

1 reference

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Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques

12 July 2018

1 reference

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Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

12 July 2018

1 reference

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Addition of a photocrosslinking amino acid to the genetic code of Escherichiacoli

12 July 2018

1 reference

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Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

12 July 2018

1 reference

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Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization

12 July 2018

1 reference

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Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins

12 July 2018

1 reference

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Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion

12 July 2018

1 reference

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Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation

12 July 2018

1 reference

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Leginon: an automated system for acquisition of images from vitreous ice specimens.

12 July 2018

1 reference

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Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies

12 July 2018

1 reference

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

12 July 2018

1 reference

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Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

12 July 2018

1 reference

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

12 July 2018

1 reference

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Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

12 July 2018

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Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Three-dimensional reconstruction of single particles embedded in ice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Tyrosine bioconjugation through aqueous ene-type reactions: a click-like reaction for tyrosine

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4468504

In vivo efficacy of anti-glycoprotein 41, but not anti-glycoprotein 120, immunotoxins in a mouse model of HIV infection

25 September 2018

1 reference

12 December 2020

Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base

1 reference

12 December 2020

p-Azidophenylglyoxal. A heterobifunctional photoactivable cross-linking reagent selective for arginyl residues

1 reference

12 December 2020

Expression and Characterization of CD4-IgG2, a Novel Heterotetramer That Neutralizes Primary HIV Type 1 Isolates

1 reference

12 December 2020

Conservation of HIV-1 gp120 neutralizing epitopes after formalin inactivation

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.03738-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878116%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

25878116

1 reference