(Q35757227)

https://doi.org/10.2337/db20-rt10d

10 August 2017

1 reference

29 December 2023

title

G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity (English)

1 reference

G protein-coupled receptor

10 August 2017

main subject

0 references

0 references

1 reference

Rocio Vila-Bedmar

3

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Sonia Fernández-Veledo

object named as

Sonia Fernández-Veledo

8

0 references

Guillermo Zalba

object named as

Guillermo Zalba

5

0 references

author name string

Lucia Garcia-Guerra

1

1 reference

10 August 2017

Iria Nieto-Vazquez

2

1 reference

10 August 2017

María Jurado-Pueyo

4

1 reference

10 August 2017

Javier Díez

6

1 reference

10 August 2017

Cristina Murga

7

1 reference

10 August 2017

Federico Mayor

9

1 reference

10 August 2017

Margarita Lorenzo

10

1 reference

10 August 2017

language of work or name

English

0 references

publication date

13 July 2010

1 reference

10 August 2017

1 reference

10 August 2017

volume

59

1 reference

10 August 2017

issue

10

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10 August 2017

page(s)

2407-2417

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

10 August 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance

2 October 2017

1 reference

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c-Jun N-terminal kinase 1/2 activation by tumor necrosis factor-alpha induces insulin resistance in human visceral but not subcutaneous adipocytes: reversal by liver X receptor agonists

2 October 2017

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GRK mythology: G-protein receptor kinases in cardiovascular disease

2 October 2017

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Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.

2 October 2017

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Insulin action on glucose transporters through molecular switches, tracks and tethers

2 October 2017

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IRS1-independent defects define major nodes of insulin resistance

2 October 2017

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Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes

2 October 2017

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Endocrine functions of adipose tissue

2 October 2017

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Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.

2 October 2017

1 reference

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GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells

2 October 2017

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The GLUT4 glucose transporter

2 October 2017

1 reference

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Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance

2 October 2017

1 reference

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The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling

2 October 2017

1 reference

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Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2

2 October 2017

1 reference

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GRKs and arrestins: regulators of migration and inflammation

2 October 2017

1 reference

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From mice to men: insights into the insulin resistance syndromes

2 October 2017

1 reference

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Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease

2 October 2017

1 reference

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Signalling role of adipose tissue: adipokines and inflammation in obesity

2 October 2017

1 reference

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Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats

2 October 2017

1 reference

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GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation

2 October 2017

1 reference

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Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes

2 October 2017

1 reference

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Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

2 October 2017

1 reference

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Beta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

LiSa-2, a novel human liposarcoma cell line with a high capacity for terminal adipose differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Co-culture with fat cells induces cellular insulin resistance in primary hepatocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Effect of age and moderate food restriction on insulin sensitivity in Wistar rats: role of adiposity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-alpha induction of p38 and p42/p44 mitogen-activated protein kinases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

The trimeric GTP-binding protein (G(q)/G(11)) alpha subunit is required for insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279564

Insulin signaling in health and disease

25 September 2018

1 reference

12 December 2020

Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure

1 reference

12 December 2020

Inflammation and insulin resistance

1 reference

12 December 2020

GRK2-dependent desensitization downstream of G proteins

1 reference

12 December 2020

Insulin resistance associated to obesity: the link TNF-alpha

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-0771

1 reference

10 August 2017

1 reference

10 August 2017

1 reference