(Q37578545)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Molecular mechanisms involved in obesity-associated insulin resistance: therapeutical approach (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1 reference

1 reference

Sonia Fernández-Veledo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

María Alonso-Chamorro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Iria Nieto-Vazquez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Rocio Vila-Bedmar

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Lucia Garcia-Guerra

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Margarita Lorenzo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

Archives of Physiology and Biochemistry

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

227-239

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

5 February 2020

cites work

1 reference

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The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones

21 January 2018

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Postprandial hypertriglyceridemia and insulin resistance in normoglycemic first-degree relatives of patients with type 2 diabetes.

21 January 2018

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Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes

21 January 2018

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Central role of the adipocyte in insulin resistance

21 January 2018

1 reference

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MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Liver x receptors: potential novel targets in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

21 January 2018

1 reference

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Interleukin-6 and insulin sensitivity: friend or foe?

21 January 2018

1 reference

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Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

21 January 2018

1 reference

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Obesity and lipodystrophy--where do the circles intersect?

21 January 2018

1 reference

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Activation of liver X receptors promotes lipid accumulation but does not alter insulin action in human skeletal muscle cells.

21 January 2018

1 reference

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Identification and importance of brown adipose tissue in adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Phosphorylation of IRS1 at serine 307 and serine 312 in response to insulin in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

21 January 2018

1 reference

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Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Innate immunity, insulin resistance and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Liver X receptor agonists ameliorate TNFalpha-induced insulin resistance in murine brown adipocytes by downregulating protein tyrosine phosphatase-1B gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Adipose tissue as a buffer for daily lipid flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-alpha induction of p38 and p42/p44 mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

The GLUT4 glucose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Roles of plasma interleukin-6 and tumor necrosis factor-alpha and FFA and TG in the development of insulin resistance induced by high-fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Perilipin expression in human adipose tissue is elevated with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Adipose tissue as an endocrine organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Mechanisms of nutritional and hormonal regulation of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

21 January 2018

1 reference

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Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

21 January 2018

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

1 reference

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Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

The perils of portliness: causes and consequences of visceral adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Unexpected evidence for active brown adipose tissue in adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Modulation of insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Thiazolidinediones: effects on insulin resistance and the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Mapping of early signaling events in tumor necrosis factor-alpha -mediated lipolysis in human fat cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 induces cellular insulin resistance in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

IL-6 and TNF-alpha expression in, and release from, contracting human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

The central role of perilipin a in lipid metabolism and adipocyte lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Rosiglitazone up-regulates lipoprotein lipase, hormone-sensitive lipase and uncoupling protein-1, and down-regulates insulin-induced fatty acid synthase gene expression in brown adipocytes of Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Signalling role of adipose tissue: adipokines and inflammation in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Activation of opioid mu-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6 stimulates lipolysis and fat oxidation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Interleukin-6-deficient mice develop mature-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Muscle-specific Pten deletion protects against insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450903164330

10.1080/13813450903164330

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19673658%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference