(Q35758833)

10 August 2017

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title

Control of glycaemia: from molecules to men. Minkowski Lecture 2003. (English)

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10 August 2017

1

Stumvoll M

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10 August 2017

28 April 2004

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10 August 2017

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10 August 2017

47

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10 August 2017

5

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10 August 2017

770-781

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https://scigraph.springernature.com/pub.10.1007/s00125-004-1400-0

10 August 2017

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12 December 2020

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

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Peroxisome proliferator-activated receptors: nuclear control of metabolism

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12 December 2020

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells

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12 December 2020

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians

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12 December 2020

Evidence for gene-nutrient interaction at the PPARgamma locus.

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12 December 2020

Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.

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12 December 2020

Calpain 10: the first positional cloning of a gene for type 2 diabetes?

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12 December 2020

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes

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12 December 2020

Adiponectin and protection against type 2 diabetes mellitus

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Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study.

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Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

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12 December 2020

Thiazolidinediones in the treatment of insulin resistance and type II diabetes

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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

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The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.

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Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

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Allostasis, homeostats, and the nature of stress

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Insulin sensitivity and insulin secretion in monozygotic and dizygotic twins.

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Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging

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Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families

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Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach

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Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

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12 December 2020

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

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Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals.

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12 December 2020

Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization

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12 December 2020

PPARgamma, the ultimate thrifty gene

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12 December 2020

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

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12 December 2020

The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects

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12 December 2020

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

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12 December 2020

Genetic dissection of complex traits

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12 December 2020

Genomic structure and mutations in adipose-specific gene, adiponectin

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Autoimmune diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult): definition, characterization, and potential prevention

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Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity.

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12 December 2020

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

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12 December 2020

Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians

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12 December 2020

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12 December 2020

Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

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12 December 2020

Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin

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12 December 2020

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

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12 December 2020

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

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12 December 2020

A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.

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Splanchnic and renal metabolism of insulin in human subjects: a dose-response study

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12 December 2020

Thiazolidinediones: an update.

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12 December 2020

Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism

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12 December 2020

The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans

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12 December 2020

Interaction between a peroxisome proliferator-activated receptor gene polymorphism and dietary fat intake in relation to body mass

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12 December 2020

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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12 December 2020

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

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12 December 2020

Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis

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12 December 2020

Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms

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12 December 2020

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

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12 December 2020

Adiponectin and development of type 2 diabetes in the Pima Indian population

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12 December 2020

UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

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12 December 2020

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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12 December 2020

Leptin-replacement therapy for lipodystrophy.

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12 December 2020

Maternally inherited diabetes and deafness: a new diabetes subtype

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12 December 2020

Protective and damaging effects of stress mediators

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12 December 2020

Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism

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12 December 2020

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

1 reference

12 December 2020

Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.

1 reference

12 December 2020

Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus

1 reference

12 December 2020

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

12 December 2020

Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene is associated with increased antilipolytic insulin sensitivity

1 reference

12 December 2020

Accurate assessment of beta-cell function: the hyperbolic correction

1 reference

12 December 2020

The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

1 reference

12 December 2020

Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance

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12 December 2020

The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism

1 reference

12 December 2020

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

1 reference

12 December 2020

Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein?

1 reference

12 December 2020

The perils of portliness: causes and consequences of visceral adiposity

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12 December 2020

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

1 reference

12 December 2020

The PPARgamma2 polymorphism pro12Ala is associated with better insulin sensitivity in the offspring of type 2 diabetic patients.

1 reference

12 December 2020

Plasma adiponectin and endogenous glucose production in humans

1 reference

12 December 2020

Glitazones: clinical effects and molecular mechanisms

1 reference

12 December 2020

Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala

1 reference

12 December 2020

Effects of free fatty acids on gluconeogenesis and autoregulation of glucose production in type 2 diabetes

1 reference

12 December 2020

The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

1 reference

12 December 2020

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

1 reference

12 December 2020

Insulin degradation: progress and potential

1 reference

12 December 2020

Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.

1 reference

12 December 2020

Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation

1 reference

12 December 2020

Longitudinal study on pubertal insulin resistance

1 reference

12 December 2020

CEACAM1 regulates insulin clearance in liver

1 reference

12 December 2020

Fat metabolism in human obesity

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12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

1 reference

12 December 2020

10.1007/S00125-004-1400-0

Identifiers

DOI

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10 August 2017

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PubMed ID

15114471