(Q35790611)

English

Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

scientific article published on 2 May 2007

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice (English)

1 reference

Europe PubMed Central

10 August 2017

0 references

traumatic brain injury

0 references

1 reference

based on heuristic

inferred from title

Denise Harhausen

3

object named as

Denise Harhausen

0 references

9

object named as

Peter A Ward

1 reference

Europe PubMed Central

10 August 2017

Daniel Rittirsch

8

object named as

Daniel Rittirsch

1 reference

Europe PubMed Central

10 August 2017

V Michael Holers

10

object named as

V Michael Holers

1 reference

Europe PubMed Central

10 August 2017

author name string

Iris Leinhase

1

1 reference

Europe PubMed Central

10 August 2017

Michal Rozanski

2

1 reference

Europe PubMed Central

10 August 2017

Denise Harhausen

3

1 reference

Europe PubMed Central

10 August 2017

Joshua M Thurman

4

1 reference

Europe PubMed Central

10 August 2017

Oliver I Schmidt

5

1 reference

Europe PubMed Central

10 August 2017

Amir M Hossini

6

1 reference

Europe PubMed Central

10 August 2017

Mohy E Taha

7

1 reference

Europe PubMed Central

10 August 2017

Wolfgang Ertel

11

1 reference

Europe PubMed Central

10 August 2017

Philip F Stahel

12

1 reference

Europe PubMed Central

10 August 2017

publication date

2 May 2007

1 reference

Europe PubMed Central

10 August 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

10 August 2017

4

1 reference

Europe PubMed Central

10 August 2017

13

1 reference

Europe PubMed Central

10 August 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-4-13

0 references

The role of the complement system in CNS inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Neuroprotection targets after traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

The central role of the alternative complement pathway in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

The role of inflammation in CNS injury and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Herbal complement inhibitors in the treatment of neuroinflammation: future strategy for neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

IL-18: a key player in neuroinflammation and neurodegeneration?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

The alternative pathway of complement in disease: opportunities for therapeutic targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Innate immunity and brain inflammation: the key role of complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

"Eat me" and "don't eat me" signals govern the innate immune response and tissue repair in the CNS: emphasis on the critical role of the complement system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Pharmacology of traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Tailoring anti-complement therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Clinical trials in head injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Complement anaphylatoxin receptors on neurons: new tricks for old receptors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Clinical trials in head injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Why have recent trials of neuroprotective agents in head injury failed to show convincing efficacy? A pragmatic analysis and theoretical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Controlling the complement system in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

The role of complement in disorders of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

An experimental model of closed head injury in mice: pathophysiology, histopathology, and cognitive deficits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

27 July 2018

Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Evaluation of pharmacological treatment strategies in traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Administration of vaccinia virus complement control protein shows significant cognitive improvement in a mild injury model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Neuroprotection from complement-mediated inflammatory damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

A CRASH landing in severe head injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Clinical trials in traumatic brain injury: lessons for the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Vaccinia virus complement control protein enhances functional recovery after traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

A peptide derived from activity-dependent neuroprotective protein (ADNP) ameliorates injury response in closed head injury in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Elevated levels of the complement components C3 and factor B in ventricular cerebrospinal fluid of patients with traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867808

25 September 2018

Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the complement system in traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of soluble complement receptor-1 on neutrophil accumulation after traumatic brain injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of C5a in the absence of C3: a new complement activation pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of C5a receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Closed head injury--an inflammatory disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17474994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-4-13

1 reference

Europe PubMed Central

10 August 2017

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0 references

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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