(Q35792726)

10 August 2017

title

Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress (English)

1 reference

10 August 2017

Timothy D Warner

5

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Masahiko Negishi

object named as

Masahiko Negishi

6

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author name string

Karen E Swales

1

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10 August 2017

Rick Moore

2

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10 August 2017

Nicola J Truss

3

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10 August 2017

Arthur Tucker

4

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10 August 2017

David Bishop-Bailey

7

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10 August 2017

publication date

13 December 2011

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10 August 2017

published in

Cardiovascular Research

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10 August 2017

volume

93

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10 August 2017

issue

4

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10 August 2017

page(s)

674-681

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3291088/fullTextXML

inferred from PubMed Central ID database lookup

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

12 July 2018

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HMG-CoA reductase inhibitors and P-glycoprotein modulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

12 July 2018

1 reference

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Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element

12 July 2018

1 reference

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Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?

12 July 2018

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Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture

12 July 2018

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

12 July 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

12 July 2018

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The vascular endothelium: a survey of some newly evolving biochemical and physiological features

12 July 2018

1 reference

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Lipogenesis in arterial wall and vascular smooth muscle cells of Psammomys obesus: its regulation and abnormalities in diabetes.

12 July 2018

1 reference

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Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Aspirin and the in vitro linear relationship between thromboxane A2-mediated platelet aggregation and platelet production of thromboxane A2.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Lipid metabolism and molecular changes in normal and atherosclerotic vessels.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291088

Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries

25 September 2018

1 reference

12 December 2020

Time-dependent expression of cytochrome P450 genes in primary cultures of well-differentiated human hepatocytes

1 reference

12 December 2020

In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

1 reference

12 December 2020

Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2

1 reference

12 December 2020

Lipophilic statins induce apoptosis of human vascular smooth muscle cells

1 reference

12 December 2020

Impact of P-glycoprotein on clopidogrel absorption

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVR330

1 reference

10 August 2017

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10 August 2017

1 reference