(Q35794571)

10 August 2017

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title

Cholesterol efflux as a critical component of Alzheimer's disease pathogenesis (English)

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10 August 2017

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G William Rebeck

1

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10 August 2017

publication date

1 January 2004

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Journal of Molecular Neuroscience

10 August 2017

published in

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10 August 2017

volume

23

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10 August 2017

issue

3

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10 August 2017

page(s)

219-224

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https://scigraph.springernature.com/pub.10.1385/jmn:23:3:219

10 August 2017

exact match

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cites work

24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

1 reference

12 December 2020

Statins and the risk of dementia

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12 December 2020

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

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12 December 2020

Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury

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12 December 2020

Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes

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12 December 2020

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

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12 December 2020

Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease

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12 December 2020

Cyp46 (24S-cholesterol hydroxylase): a genetic risk factor for Alzheimer disease

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12 December 2020

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice

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12 December 2020

Apolipoprotein E polymorphism and atherosclerosis

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12 December 2020

Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member

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12 December 2020

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

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12 December 2020

Dissociation of apolipoprotein and apolipoprotein receptor response to lesion in the rat brain: an in situ hybridization study

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12 December 2020

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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12 December 2020

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

1 reference

12 December 2020

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

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12 December 2020

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

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12 December 2020

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

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12 December 2020

Statin therapy for Alzheimer's disease: will it work?

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12 December 2020

Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

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12 December 2020

Alzheimer's disease: the cholesterol connection

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12 December 2020

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

1 reference

12 December 2020

Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism

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12 December 2020

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

1 reference

12 December 2020

Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture

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12 December 2020

ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol

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12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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12 December 2020

A detergent-insoluble membrane compartment contains A beta in vivo

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12 December 2020

Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

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12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

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12 December 2020

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease

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12 December 2020

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

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12 December 2020

Head injury and the risk of AD in the MIRAGE study

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12 December 2020

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

1 reference

12 December 2020

Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis.

1 reference

12 December 2020

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

1 reference

12 December 2020

The high density lipoprotein- and apolipoprotein A-I-induced mobilization of cellular cholesterol is impaired in fibroblasts from Tangier disease subjects

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12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

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12 December 2020

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

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12 December 2020

Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system

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12 December 2020

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

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12 December 2020

Characterization of four lipoprotein classes in human cerebrospinal fluid

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12 December 2020

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

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12 December 2020

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

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12 December 2020

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

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12 December 2020

Oxysterol biosynthetic enzymes

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12 December 2020

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

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12 December 2020

Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide

1 reference

12 December 2020

Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid

1 reference

12 December 2020

Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease

1 reference

12 December 2020

HDL-mediated efflux of intracellular cholesterol is impaired in fibroblasts from Tangier disease patients

1 reference

12 December 2020

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

1 reference

12 December 2020

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

1 reference

12 December 2020

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

1 reference

12 December 2020

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

12 December 2020

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

1 reference

12 December 2020

Identifiers

DOI

10.1385/JMN:23:3:219

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Dimensions Publication ID

10 August 2017

1026273337

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