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Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER.
scientific article published on 15 October 2015
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Europe PubMed Central
PMCID
4608161
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
title
Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
main subject
G protein-coupled receptor
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estrogen
1 reference
based on heuristic
inferred from title
author
Eric R Prossnitz
series ordinal
2
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stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
author name string
Erin Zekas
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1
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Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
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27 February 2020
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English
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publication date
15 October 2015
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Europe PubMed Central
PMCID
4608161
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
published in
BMC Cancer
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Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
volume
15
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Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
page(s)
702
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stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4608161/fullTextXML
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exact match
https://scigraph.springernature.com/pub.10.1186/s12885-015-1699-6
0 references
cites work
What have we learned about GPER function in physiology and disease from knockout mice?
1 reference
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PubMed Central
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27 July 2018
International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators
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27 July 2018
Emerging roles of GPER in diabetes and atherosclerosis
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27 July 2018
G protein-coupled estrogen receptor protects from atherosclerosis
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27 July 2018
G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis
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Estrogen receptor signaling during vertebrate development
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27 July 2018
Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth
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27 July 2018
GPER Function in Breast Cancer: An Overview
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27 July 2018
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth
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27 July 2018
GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
Oestrogen receptors in breast cancer: basic mechanisms and clinical implications.
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27 July 2018
The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness
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27 July 2018
Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα)
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27 July 2018
The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T-cell population under TH17-polarizing conditions
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27 July 2018
Mammary gland development
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27 July 2018
Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin
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27 July 2018
The G-protein-coupled estrogen receptor GPER in health and disease
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27 July 2018
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells
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PubMed Central
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Harnessing the tumor suppressor function of FOXO as an alternative therapeutic approach in cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
Non-nuclear estrogen receptor signaling in the endothelium
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
Reciprocal control of cell proliferation and migration
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PubMed Central
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Hormone action in the mammary gland
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PubMed Central
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The emerging mechanisms of isoform-specific PI3K signalling
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27 July 2018
Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair
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27 July 2018
The AMPK-FoxO3A axis as a target for cancer treatment
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27 July 2018
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608161
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27 July 2018
17β-estradiol enhances α(5) integrin subunit gene expression through ERα-Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells
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27 July 2018
Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells
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27 July 2018
In vivo effects of a GPR30 antagonist
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27 July 2018
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication
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27 July 2018
The FoxO code
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27 July 2018
A brief introduction to FOXOlogy
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27 July 2018
Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis
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27 July 2018
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.
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27 July 2018
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27 July 2018
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation
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27 July 2018
Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.
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27 July 2018
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27 July 2018
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
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27 July 2018
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
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27 July 2018
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
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27 July 2018
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells
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27 July 2018
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27 July 2018
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
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27 July 2018
Estrogen biology: new insights into GPER function and clinical opportunities
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25 September 2018
Estrogen and pure antiestrogen fulvestrant (ICI 182 780) augment cell-matrigel adhesion of MCF-7 breast cancer cells through a novel G protein coupled estrogen receptor (GPR30)-to-calpain signaling axis
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25 September 2018
GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state
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25 September 2018
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25 September 2018
Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1.
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25 September 2018
Characterization of intracellular translocation of Forkhead transcription factor O (FoxO) members induced by NGF in PC12 cells
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25 September 2018
Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts
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25 September 2018
Unravelling the tumor-suppressive functions of FOXO proteins
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25 September 2018
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25 September 2018
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
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25 September 2018
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25 September 2018
Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants.
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25 September 2018
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
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25 September 2018
G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26470790
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Primary extraosseous Ewing sarcoma of the lung in children
1 reference
stated in
COCI
retrieved
12 January 2024
reference URL
https://opencitations.net/index/api/v1/citations/10.3332/ECANCER.2013.312
Identifiers
DOI
10.1186/S12885-015-1699-6
1 reference
stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
Dimensions Publication ID
1048921029
0 references
PMCID
4608161
1 reference
stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
PubMed ID
26470790
1 reference
stated in
Europe PubMed Central
PMCID
4608161
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26470790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
ResearchGate publication ID
283812751
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