(Q35830589)

English

FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance

scientific article published on 8 July 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

0 references

insulin resistance

1 reference

based on heuristic

inferred from title

object named as

Pingping Li

4

0 references

author name string

Barbara Bernardo

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Min Lu

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Gautam Bandyopadhyay

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yingjiang Zhou

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jie Huang

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Nancy Levin

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Eva M Tomas

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Roberto A Calle

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Derek M Erion

10

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Timothy P Rolph

11

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Martin Brenner

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Saswata Talukdar

13

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

8 July 2015

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Scientific Reports

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Europe PubMed Central

PMC publication ID

10 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

11382

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 July 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Fibroblast growth factor 21 improves insulin sensitivity and synergizes with insulin in human adipose stem cell-derived (hASC) adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF21-based pharmacotherapy--potential utility for metabolic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Fundamentals of FGF19 & FGF21 action in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Between brown and white: novel aspects of adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Fibroblast growth factor 21 corrects obesity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

FGF-21 as a novel metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Brown adipose tissue: function and physiological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

Glucose metabolism in isolated brown adipocytes under beta-adrenergic stimulation. Quantitative contribution of glucose to total thermogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

11 July 2018

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Fibroblast growth factor 21 improves insulin resistance and ameliorates renal injury in db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Morphology of pancreatic islets: a time course of pre-diabetes in Zucker fatty rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4495598

24 September 2018

Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26153793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The browning of white adipose tissue: some burning issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/26153793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP11382

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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