(Q35839881)

English

Early Life Exposure to Fructose Alters Maternal, Fetal and Neonatal Hepatic Gene Expression and Leads to Sex-Dependent Changes in Lipid Metabolism in Rat Offspring

scientific article published on 12 November 2015

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Early Life Exposure to Fructose Alters Maternal, Fetal and Neonatal Hepatic Gene Expression and Leads to Sex-Dependent Changes in Lipid Metabolism in Rat Offspring (English)

1 reference

Europe PubMed Central

10 August 2017

object named as

Zoe E Clayton

1

0 references

2

object named as

Mark H Vickers

1 reference

Europe PubMed Central

10 August 2017

Deborah Sloboda

5

object named as

Deborah M Sloboda

1 reference

Europe PubMed Central

10 August 2017

4

object named as

Cassandra Yap

1 reference

Europe PubMed Central

10 August 2017

author name string

Angelica Bernal

3

1 reference

Europe PubMed Central

10 August 2017

language of work or name

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publication date

12 November 2015

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

11

1 reference

Europe PubMed Central

10 August 2017

e0141962

1 reference

Europe PubMed Central

10 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults

1 reference

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Early life exposure to fructose and offspring phenotype: implications for long term metabolic homeostasis

1 reference

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Maternal gestational weight gain and offspring risk for childhood overweight or obesity.

1 reference

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Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis

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CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1.

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High fat diet and in utero exposure to maternal obesity disrupts circadian rhythm and leads to metabolic programming of liver in rat offspring

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Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies.

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Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity

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Fructose, pregnancy and later life impacts

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Fructose-induced hyperuricemia is associated with a decreased renal uric acid excretion in humans

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Maternal and paternal body mass index and offspring obesity: a systematic review

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The obesogenic effect of high fructose exposure during early development

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Fructose during pregnancy affects maternal and fetal leptin signaling

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Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver

1 reference

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Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

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Maternal obesity, gestational weight gain and diet as determinants of offspring long term health

1 reference

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IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

1 reference

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Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice

1 reference

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SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

1 reference

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AMPK: a nutrient and energy sensor that maintains energy homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation

1 reference

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ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

11 July 2018

The epidemiology of uric acid and fructose

1 reference

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AMP-activated protein kinase: nature's energy sensor

1 reference

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Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake

1 reference

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11 July 2018

Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

11 July 2018

Fructose induced lipogenesis: from sugar to fat to insulin resistance

1 reference

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Molecular mechanism of NLRP3 inflammasome activation

1 reference

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VLDL hydrolysis by LPL activates PPAR-alpha through generation of unbound fatty acids

1 reference

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Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

1 reference

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The inflammasomes

1 reference

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Protein malnutrition during pregnancy in C57BL/6J mice results in offspring with altered circadian physiology before obesity

1 reference

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AMPK and SIRT1: a long-standing partnership?

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Dietary sugars stimulate fatty acid synthesis in adults

1 reference

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Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

1 reference

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SREBP-1c transcription factor and lipid homeostasis: clinical perspective

1 reference

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1 reference

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Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Comparative aspects of lipid metabolism: impact on contemporary research and use of animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

11 July 2018

A causal role for uric acid in fructose-induced metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

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11 July 2018

Effects of dietary fructose on plasma lipids in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

11 July 2018

Facilitative glucose transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Dietary sugars and lipid metabolism in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Effect of oral fructose on urate production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Direct enzymatic procedure for the determination of liver glycogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Fructose and purine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Fructose and sucrose feeding during pregnancy and lactation in rats changes maternal and pup fuel metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Fructose intake during pregnancy up-regulates the expression of maternal and fetal hepatic sterol regulatory element-binding protein-1c in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Supplementation of bitter melon to rats fed a high-fructose diet during gestation and lactation ameliorates fructose-induced dyslipidemia and hepatic oxidative stress in male offspring.

1 reference

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Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Maternal fructose intake during pregnancy and lactation alters placental growth and leads to sex-specific changes in fetal and neonatal endocrine function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Peroxisome proliferator-activated receptor alpha target genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Early undernutrition attenuates the inflammatory response in adult rat offspring

1 reference

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Taurine supplementation enhances nutrient-induced insulin secretion in pancreatic mice islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Dietary fructose consumption among US children and adults: the Third National Health and Nutrition Examination Survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

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Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Female rats are protected against fructose-induced changes in metabolism and blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Taurine attenuates hypertension and improves insulin sensitivity in the fructose-fed rat, an animal model of insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Low dose fructose ingestion during gestation and lactation affects carbohydrate metabolism in rat dams and their offspring.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Blood lipid distribution of hyperinsulinemic men consuming three levels of fructose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643022

24 September 2018

Effect of fructose administration on serum urate levels in the uricase inhibited rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/26562417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholestasis induced by total parenteral nutrition: effects of the addition of Taurine (Tauramin®) on hepatic function parameters; possible synergistic action of structured lipids (SMOFlipid®)

1 reference

https://pubmed.ncbi.nlm.nih.gov/26562417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telmisartan increases lipoprotein lipase expression via peroxisome proliferator-activated receptor-alpha in HepG2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26562417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fructose-induced hyperuricaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26562417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0141962

1 reference

Europe PubMed Central

10 August 2017

2015PLoSO..1041962C

0 references

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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