(Q35843730)

10 August 2017

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title

Targeting mTOR-mediated survival signals in anticancer therapeutic strategies (English)

1 reference

10 August 2017

David A Foster

1

1 reference

10 August 2017

publication date

1 August 2004

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Expert Review of Anticancer Therapy

10 August 2017

published in

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10 August 2017

volume

4

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10 August 2017

issue

4

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10 August 2017

page(s)

691-701

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A Restriction Point for Control of Normal Animal Cell Proliferation

10 August 2017

cites work

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Creation of human tumour cells with defined genetic elements

21 January 2018

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Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

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The machinery of programmed cell death.

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

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TOR, a central controller of cell growth

21 January 2018

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The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

21 January 2018

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Will mTOR inhibitors make it as cancer drugs?

21 January 2018

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A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling

21 January 2018

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Does the ribosome translate cancer?

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

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Akt regulates growth by directly phosphorylating Tsc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Rheb promotes cell growth as a component of the insulin/TOR signalling network

21 January 2018

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Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

21 January 2018

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Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells

21 January 2018

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Induction of phosphatidic acid by fibroblast growth factor in cultured baby hamster kidney fibroblasts.

21 January 2018

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Phospholipase D and RalA cooperate with the epidermal growth factor receptor to transform 3Y1 rat fibroblasts

21 January 2018

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Neoplastic transformation and tumorigenesis associated with overexpression of phospholipase D isozymes in cultured murine fibroblasts.

21 January 2018

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Transmodulation between Phospholipase D and c-Src Enhances Cell Proliferation

21 January 2018

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Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling

21 January 2018

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Roles of phospholipase D in apoptosis and pro-survival

21 January 2018

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Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.

21 January 2018

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Mechanisms of resistance to STI571 in Philadelphia chromosome-associated leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

The significance of unstable chromosomes in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Cancer revoked: oncogenes as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

Phospholipase D-structure, regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.4.691

21 January 2018

Identifiers

DOI

10.1586/14737140.4.4.691

1 reference

10 August 2017

1 reference