(Q35859412)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

ChEBI release 2020-05-28

ChEBI ID

29806

author

Hugh Christian Watkins

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Houman Ashrafian

1

1 reference

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25 January 2020

Gabor Czibik

2

1 reference

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25 January 2020

Dunja Aksentijevic

4

1 reference

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25 January 2020

Anthony C Smith

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Michael S Dodd

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jennifer A. Kirwan

8

1 reference

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25 January 2020

Arash Yavari

12

1 reference

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25 January 2020

Daniel A Tennant

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Craig Lygate

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Mogens Johannsen

23

1 reference

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25 January 2020

Rajesh K Kharbanda

24

1 reference

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25 January 2020

Rafael de Cabo

27

1 reference

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25 January 2020

Mark R. Viant

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Patrick J Pollard

33

1 reference

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25 January 2020

Damian J. Tyler

34

1 reference

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25 January 2020

author name string

Mohamed Bellahcene

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Sarah J Mitchell

6

1 reference

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25 January 2020

Jonathan J Byrne

9

1 reference

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25 January 2020

Christian Ludwig

10

1 reference

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25 January 2020

Henrik Isackson

11

1 reference

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25 January 2020

Nicolaj B Støttrup

13

1 reference

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25 January 2020

Hussain Contractor

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Thomas J Cahill

15

1 reference

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25 January 2020

Natasha Sahgal

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Daniel R Ball

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Rune I D Birkler

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Iain Hargreaves

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

John Land

21

1 reference

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25 January 2020

Stefan Neubauer

25

1 reference

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25 January 2020

Charles Redwood

26

1 reference

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25 January 2020

Ismayil Ahmet

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Mark Talan

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Ulrich L Günther

30

1 reference

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25 January 2020

Alan J Robinson

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

1 March 2012

1 reference

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25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

15

1 reference

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25 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

361-371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

25 January 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

11 July 2018

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Genetic analysis of cytoprotective functions supported by graded expression of Keap1

11 July 2018

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Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors

11 July 2018

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Hydrogen sulfide mediates cardioprotection through Nrf2 signaling

11 July 2018

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11 July 2018

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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

11 July 2018

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Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice

11 July 2018

1 reference

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Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

11 July 2018

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Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1

11 July 2018

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11 July 2018

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11 July 2018

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PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

11 July 2018

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11 July 2018

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11 July 2018

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Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

11 July 2018

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Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

11 July 2018

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11 July 2018

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Nrf2-Keap1 defines a physiologically important stress response mechanism

11 July 2018

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Efficacy of preconditioning should be gauged by reduction of infarction

11 July 2018

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11 July 2018

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

11 July 2018

1 reference

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Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

11 July 2018

1 reference

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Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene

11 July 2018

1 reference

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Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation

11 July 2018

1 reference

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Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis

11 July 2018

1 reference

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Anaerobic rat heart. Effects of glucose and tricarboxylic acid-cycle metabolites on metabolism and physiological performance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Induction of glutathione transferases and NAD(P)H:quinone reductase by fumaric acid derivatives in rodent cells and tissues.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

In Vitro and In Vivo Characteristics of a Heme Oxygenase Inhibitor: ZnBG

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Multiple end products of anaerobiosis in diving vertebrates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Metabolic responses to cardiac hypoxia. Increased production of succinate by rabbit papillary muscles

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Glucose-insulin-potassium reduces the incidence of low cardiac output episodes after aortic valve replacement for aortic stenosis in patients with left ventricular hypertrophy: results from the Hypertrophy, Insulin, Glucose, and Electrolytes (HINGE)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

4-hydroxy-2-nonenal protects against cardiac ischemia-reperfusion injury via the Nrf2-dependent pathway

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

A UPLC-MS/MS application for profiling of intermediary energy metabolites in microdialysis samples--a method for high-throughput

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Glutamate release predicts ongoing myocardial ischemia of rat hearts

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314920

Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis

24 September 2018

1 reference

12 December 2020

Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice

1 reference

12 December 2020

Augmented conversion of aspartate and glutamate to succinate during anoxia in rabbit heart

1 reference

12 December 2020

Tricarboxylic acid cycle metabolites during ischemia in isolated perfused rat heart

1 reference

12 December 2020

Evidence for succinate production by reduction of fumarate during hypoxia in isolated adult rat heart cells

1 reference

12 December 2020

Pathways of succinate formation and their contribution to improvement of cardiac function in the hypoxic rat heart

1 reference

12 December 2020

Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia

1 reference

12 December 2020

Dynamics of myocardial metabolism in the preconditioned porcine heart studied using continuous microdialysis

1 reference

12 December 2020

Effects and metabolism of fumarate in the perfused rat heart. A 13C mass isotopomer study

1 reference

12 December 2020

Expression of heme oxygenase-1 can determine cardiac xenograft survival

1 reference

12 December 2020

Systemic Effects of Orally-Administered Zinc and Tin (IV) Metalloporphyrins on Heme Oxygenase Expression in Mice

1 reference

12 December 2020

Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids

1 reference

12 December 2020

10.1016/J.CMET.2012.01.017

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405071%20AND%20SRC:MED&resulttype=core&format=json