(Q35859536)

English

Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation

scientific article published on 29 May 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

inflammasome complex

1 reference

based on heuristic

inferred from title

author name string

Dan Liu

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yi Wen

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Tao-Tao Tang

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Lin-Li Lv

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ri-Ning Tang

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Hong Liu

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Kun-Ling Ma

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Steve D Crowley

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Bi-Cheng Liu

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

29 May 2015

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

290

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

29

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

18018-18028

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Progression of renal injury toward interstitial inflammation and glomerular sclerosis is dependent on abnormal protein filtration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The emerging role of the inflammasome in kidney diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The proximal tubule and albuminuria: really!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Activation and regulation of the inflammasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Limited capacity of proximal tubular proteolysis in mice with proteinuria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Regulation of inflammasome signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Lysosomal function and dysfunction: mechanism and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Nucleotide-binding oligomerization domain-like receptors and inflammasomes in the pathogenesis of non-microbial inflammation and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The inflammasomes in kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

A role for mitochondria in NLRP3 inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Cubilin is essential for albumin reabsorption in the renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Molecular mechanism of NLRP3 inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The inflammasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Proteinuria and events beyond the slit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

The inflammasomes: guardians of the body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

PKB and megalin determine the survival or death of renal proximal tubule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

How does proteinuria cause progressive renal damage?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor kappaB in proximal tubule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

27 July 2018

Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Sensing and reacting to microbes through the inflammasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Receptor-mediated endocytosis in renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kappa B activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Interstitial nephritis induced by protein-overload proteinuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505048

24 September 2018

Proteinuria and interstitial injury

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.662064

21 January 2018

Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.662064

21 January 2018

Identifiers

10.1074/JBC.M115.662064

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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