(Q35875570)

10 August 2017

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title

IGF-I receptor, cell-cell adhesion, tumour development and progression (English)

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10 August 2017

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Loredana Mauro

1

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PubMed ID

15339044

10 August 2017

Eva Surmacz

series ordinal

2

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10 August 2017

1 March 2004

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Journal of Molecular Histology

10 August 2017

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10 August 2017

35

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10 August 2017

3

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10 August 2017

247-253

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E-cadherin gene mutations provide clues to diffuse type gastric carcinomas

10 August 2017

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12 December 2020

Oncogenes and the strategy of growth factors

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12 December 2020

Varying patterns of expression of insulin-like growth factors I and II and their receptors in murine mammary adenocarcinomas of different metastasizing ability

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12 December 2020

Expressed recombinant cadherins mediate cell sorting in model systems

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12 December 2020

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

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12 December 2020

Cytoskeletal and adhesion proteins as tumor suppressors

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12 December 2020

The IGF axis and hepatocarcinogenesis

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12 December 2020

The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells

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12 December 2020

Association of insulin receptor substrate-1 with integrins

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12 December 2020

Identification of c-MYC as a target of the APC pathway

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12 December 2020

The IGF system and breast cancer

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12 December 2020

Differential effects of the insulin-like growth factor I receptor on radiosensitivity and spontaneous necrosis formation of human glioblastoma cells grown in multicellular spheroids.

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12 December 2020

PLC-gamma1 is required for IGF-I protection from cell death induced by loss of extracellular matrix adhesion.

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12 December 2020

Linking colorectal cancer to Wnt signaling

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12 December 2020

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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12 December 2020

E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

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12 December 2020

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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12 December 2020

Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization

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12 December 2020

Controversies at the cytoplasmic face of the cadherin-based adhesion complex

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12 December 2020

The insulin-like growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: a new avenue for breast cancer therapy.

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12 December 2020

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

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12 December 2020

Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities

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12 December 2020

p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors

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12 December 2020

p120 catenin regulates the actin cytoskeleton via Rho family GTPases

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12 December 2020

Mechanism of STAT3 activation by insulin-like growth factor I receptor

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12 December 2020

Cadherins and tissue formation: integrating adhesion and signaling

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12 December 2020

Morphogenetic roles of classic cadherins

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12 December 2020

Dysregulation of IGF-I signaling in uterine leiomyoma

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12 December 2020

Insulin-like growth factor physiology and cancer risk

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12 December 2020

Insulin, insulin-like growth factors and colon cancer: a review of the evidence

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12 December 2020

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix

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12 December 2020

The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin

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12 December 2020

Cadherins and catenins in development

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12 December 2020

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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12 December 2020

Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk

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12 December 2020

Minireview: Integral Membrane Proteins that Function Coordinately with the Insulin-Like Growth Factor I Receptor to Regulate Intracellular Signaling

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12 December 2020

Type I insulin-like growth factor receptor function in breast cancer.

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12 December 2020

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes

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12 December 2020

Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes

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12 December 2020

Role of the IGF-I receptor in the regulation of cell-cell adhesion: implications in cancer development and progression

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12 December 2020

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

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12 December 2020

The insulin-like growth factor I receptor: a key to tumor growth?

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12 December 2020

Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells

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12 December 2020

Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction

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12 December 2020

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

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12 December 2020

A novel role for p120 catenin in E-cadherin function

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12 December 2020

Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype

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12 December 2020

E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

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12 December 2020

The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity

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12 December 2020

PKB binding proteins. Getting in on the Akt.

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12 December 2020

Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells.

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12 December 2020

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

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12 December 2020

Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor

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12 December 2020

Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro

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12 December 2020

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

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12 December 2020

Insulin-like growth factors and prostate cancer

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12 December 2020

Rho GTPases and the actin cytoskeleton

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12 December 2020

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

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12 December 2020

The IRS-signalling system: a network of docking proteins that mediate insulin action

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12 December 2020

Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors

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12 December 2020

Inhibition of RhoA by p120 catenin

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12 December 2020

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

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12 December 2020

Cadherin-catenin complex: protein interactions and their implications for cadherin function

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12 December 2020

Cell adhesion and Rho small GTPases

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12 December 2020

IRS proteins and the common path to diabetes

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12 December 2020

Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9

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12 December 2020

Frequent alterations in E-cadherin and alpha- and beta-catenin expression in human breast cancer cell lines

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12 December 2020

Defects in the regulation of beta-catenin in colorectal cancer

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12 December 2020

Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

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12 December 2020

Integrins and E-cadherin cooperate with IGF-I to induce migration of epithelial colonic cells

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12 December 2020

Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion

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12 December 2020

Inhibition of protein kinase B/Akt. implications for cancer therapy

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12 December 2020

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12 December 2020

p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.

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12 December 2020

Regulation of survival signals from the insulin-like growth factor-I receptor

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12 December 2020

p120, a novel substrate of protein tyrosine kinase receptors and of p60v-src, is related to cadherin-binding factors beta-catenin, plakoglobin and armadillo

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12 December 2020

Adhesion in development: an historical overview

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12 December 2020

Insulin-like growth factors (IGF) enhance three-dimensional (3D) growth of human glioblastomas.

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12 December 2020

Small GTP-binding proteins

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12 December 2020

Enhanced invasion and liver colonization by lung carcinoma cells overexpressing the type 1 insulin-like growth factor receptor

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12 December 2020

The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.

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12 December 2020

The protein kinase B/Akt signalling pathway in human malignancy

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12 December 2020

Function of the IGF-I receptor in breast cancer

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12 December 2020

Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion

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12 December 2020

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

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12 December 2020

Expression of E- or P-cadherin is not sufficient to modify the morphology and the tumorigenic behavior of murine spindle carcinoma cells. Possible involvement of plakoglobin

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12 December 2020

SHC-alpha5beta1 integrin interactions regulate breast cancer cell adhesion and motility

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12 December 2020

Structure and function of the type 1 insulin-like growth factor receptor.

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12 December 2020

Regulation of Rho GTPases by p120-catenin

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12 December 2020

Structural basis of cell-cell adhesion by cadherins

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12 December 2020

IGF-1 in gynaecology and obstetrics: update 2002.

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12 December 2020

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

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12 December 2020

A repeating amino acid motif shared by proteins with diverse cellular roles

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12 December 2020

Role of growth factors in pancreatic cancer.

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12 December 2020

IGF-I Receptor-induced Cell-Cell Adhesion of MCF-7 Breast Cancer Cells Requires the Expression of Junction Protein ZO-1

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12 December 2020

Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3'-kinase and formation of a p130(Cas).Crk complex

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12 December 2020

Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells

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12 December 2020

Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism

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12 December 2020

Removal of sialic acid from the surface of human MCF-7 mammary cancer cells abolishes E-cadherin-dependent cell-cell adhesion in an aggregation assay

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12 December 2020

10.1023/B:HIJO.0000032356.98363.A2

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15339044